CD47|Proteinase K|EGFR|BCMA|PD-L1|CD276|ACE2|TMPRSS2|Exosome Isolation Kits
Code | CSB-PA618786ESR2HU |
Size |
US$167Purchase it in Cusabio online store (only available for customers from the US) |
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Full Product Name | Rabbit anti-Homo sapiens (Human) CAMK2B Polyclonal antibody | ||||
Uniprot No. | Q13554 | ||||
Target Names | CAMK2B | ||||
Alternative Names | Calcium/calmodulin dependent protein kinase (CaM kinase) II beta antibody; Calcium/calmodulin dependent protein kinase II beta antibody; Calcium/calmodulin dependent protein kinase IIB antibody; Calcium/calmodulin dependent protein kinase type II beta chain antibody; calcium/calmodulin-dependent protein kinase II beta antibody; Calcium/calmodulin-dependent protein kinase type II subunit beta antibody; CAM 2 antibody; CaM kinase II beta chain antibody; CaM kinase II beta subunit antibody; CaM kinase II subunit beta antibody; CaM-kinase II beta chain antibody; CAM2 antibody; CAMK 2 antibody; CAMK 2B antibody; CaMK II beta subunit antibody; CaMK II subunit beta antibody; CaMK-II subunit beta antibody; CAMK2 antibody; CaMK2 beta antibody; Camk2b antibody; CAMKB antibody; CaMKII beta subunit antibody; CaMKIIB antibody; KCC2B_HUMAN antibody; MGC29528 antibody; Proline rich calmodulin dependent protein kinase antibody; proline rich calmodulin-dependent protein kinase antibody | ||||
Raised in | Rabbit | ||||
Species Reactivity | Human | ||||
Immunogen | Recombinant Human Calcium/calmodulin-dependent protein kinase type II subunit beta protein (1-300AA) | ||||
Immunogen Species | Homo sapiens (Human) | ||||
Conjugate | Non-conjugated | ||||
Clonality | Polyclonal | ||||
Isotype | IgG | ||||
Purification Method | Antigen Affinity Purified | ||||
Concentration | It differs from different batches. Please contact us to confirm it. | ||||
Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. | ||||
Form | Liquid | ||||
Tested Applications | ELISA, IHC | ||||
Recommended Dilution |
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Protocols | ELISA Protocol Immunohistochemistry (IHC) Protocol |
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Troubleshooting and FAQs | Antibody FAQs | ||||
Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | ||||
Lead Time | Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time. |
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Function | Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in dendritic spine and synapse formation, neuronal plasticity and regulation of sarcoplasmic reticulum Ca(2+) transport in skeletal muscle. In neurons, plays an essential structural role in the reorganization of the actin cytoskeleton during plasticity by binding and bundling actin filaments in a kinase-independent manner. This structural function is required for correct targeting of CaMK2A, which acts downstream of NMDAR to promote dendritic spine and synapse formation and maintain synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning. In developing hippocampal neurons, promotes arborization of the dendritic tree and in mature neurons, promotes dendritic remodeling. Participates in the modulation of skeletal muscle function in response to exercise. In slow-twitch muscles, is involved in regulation of sarcoplasmic reticulum (SR) Ca(2+) transport and in fast-twitch muscle participates in the control of Ca(2+) release from the SR through phosphorylation of triadin, a ryanodine receptor-coupling factor, and phospholamban (PLN/PLB), an endogenous inhibitor of SERCA2A/ATP2A2. |
Gene References into Functions |
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Subcellular Location | Cytoplasm, cytoskeleton, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, Sarcoplasmic reticulum membrane, Peripheral membrane protein, Cytoplasmic side |
Protein Families | Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily |
Tissue Specificity | Widely expressed. Expressed in adult and fetal brain. Expression is slightly lower in fetal brain. Expressed in skeletal muscle. |
Database Links |
HGNC: 1461 OMIM: 607707 KEGG: hsa:816 STRING: 9606.ENSP00000379098 UniGene: Hs.351887 |