CCT6A Antibody

Datasheet

Code	CSB-PA004865EA01HU
Size	US$166
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Image	Western Blot Positive WB detected in: Hela whole cell lysate, HepG2 whole cell lysate, U251 whole cell lysate, 293T whole cell lysate All lanes: CCT6A antibody at 4.2µg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 59, 54 kDa Observed band size: 54 kDa
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) CCT6A Polyclonal antibody

Uniprot No.

P40227

Target Names

CCT6A

Alternative Names

CCT6A antibody; CCT6 antibody; CCTZ antibody; T-complex protein 1 subunit zeta antibody; TCP-1-zeta antibody; Acute morphine dependence-related protein 2 antibody; CCT-zeta-1 antibody; HTR3 antibody; Tcp20 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human T-complex protein 1 subunit zeta protein (80-250AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The CCT6A Antibody (Product code: CSB-PA004865EA01HU) is Non-conjugated. For CCT6A Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA004865EB01HU	CCT6A Antibody, HRP conjugated	ELISA
FITC	CSB-PA004865EC01HU	CCT6A Antibody, FITC conjugated
Biotin	CSB-PA004865ED01HU	CCT6A Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:5000

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. The TRiC complex plays a role in the folding of actin and tubulin (Probable).

Gene References into Functions

High expression of CCT6A is associated with Non-Small Cell Lung Cancer. PMID: 28104536
selective inhibition of SMAD3 or CCT6A efficiently suppresses TGF-beta-mediated metastasis. Findings provide a mechanism that directs TGF-beta signaling toward its prometastatic arm and may contribute to the development of therapeutic strategies targeting TGF-beta for non-small-cell lung carcinoma. PMID: 28375158
These data suggest that CCT6A is a novel autoantigen recognized by Vdelta2 gammadelta T cells, which deepens our understanding of mechanisms in autoimmune diseases. PMID: 27489109
identified genes, which include Tcp20, may play important role in conferring radioresistance to oral squamous cell carcinoma and could be useful in identifying cases with more radioresistance PMID: 16211299

Subcellular Location

Cytoplasm.

Protein Families

TCP-1 chaperonin family

Database Links

HGNC: 1620

OMIM: 104613

KEGG: hsa:908

STRING: 9606.ENSP00000275603

UniGene: Hs.82916

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Protein Service

Gene Synthesis Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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