CPT1C Antibody, FITC conjugated

Code CSB-PA855048LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) CPT1C Polyclonal antibody
Uniprot No.
Target Names
Alternative Names
brain isoform antibody; Carnitine acyltransferase like protein 1 antibody; Carnitine acyltransferase like protein1 antibody; Carnitine O palmitoyltransferase 1 brain isoform antibody; Carnitine O palmitoyltransferase I; brain isoform antibody; Carnitine O-palmitoyltransferase 1 antibody; Carnitine O-palmitoyltransferase I antibody; Carnitine palmitoyltransferase 1; brain antibody; Carnitine palmitoyltransferase 1C antibody; Carnitine palmitoyltransferase I related C antibody; Carnitine palmitoyltransferase1C antibody; CAT L1 antibody; CATL 1 antibody; CATL1 antibody; CPT 1 like pseudogene antibody; Cpt 1c antibody; CPT 1P antibody; CPT I C antibody; CPT IC antibody; Cpt1 c antibody; CPT1 like pseudogene antibody; CPT1-B antibody; Cpt1c antibody; CPT1C_HUMAN antibody; CPT1P antibody; CPTI-B antibody; CPTIC antibody
Raised in
Species Reactivity
Recombinant Human Carnitine O-palmitoyltransferase 1, brain isoform protein (699-803AA)
Immunogen Species
Homo sapiens (Human)
Purification Method
>95%, Protein G purified
It differs from different batches. Please contact us to confirm it.
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Troubleshooting and FAQs
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

May play a role in lipid metabolic process.
Gene References into Functions
  1. Depletion of PPARalpha resulted in low CPT1C expression. PMID: 28334197
  2. CPT1C binds malonyl-CoA and long-chain acyl-CoA suggest that it is a sensor of lipid metabolism in neurons, where it appears to impact ceramide and triacylglycerol metabolism. [review] PMID: 26708865
  3. CPT1c is found in brain regions that are related to food intake and neuropsychiatric disease. CPT1c affects ceramide levels, endocannabionoids, and oxidative processes and may play an important role in various brain functions such as learning. PMID: 26041663
  4. CPT1C mutation associated with novel form of pure autosomal dominant hereditary spastic paraplegia. PMID: 25751282
  5. High grade glioblastoma is associated with increased level of ZFP57, a protein involved in gene imprinting, and aberrant expression of CPT1A and CPT1C. PMID: 24618825
  6. Data suggest that an involvement of CPT1C in cellular energy-sensing pathways and provide evidence for a role of CPT1C in hypothalamic regulation of energy homeostasis. PMID: 21961029
  7. cells can use a novel mechanism involving CPT1C and fatty acid metabolism to protect against metabolic stress PMID: 21576264
  8. CPT1c is localized in endoplasmic reticulum of neurons and has carnitine palmitoyltransferase activity PMID: 18192268
  9. Accumulation of 3-hydroxylated intermediates of long-chain fatty acids may contribute to the pathogenesis of retinopathy in MTP deficiencies. PMID: 18385088

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Involvement in disease
Spastic paraplegia 73, autosomal dominant (SPG73)
Subcellular Location
Mitochondrion outer membrane; Multi-pass membrane protein. Cell junction, synapse. Cell projection, dendrite. Cell projection, axon. Endoplasmic reticulum.
Protein Families
Carnitine/choline acetyltransferase family
Tissue Specificity
Expressed predominantly in brain and testis. Expressed in motor neurons.
Database Links

HGNC: 18540

OMIM: 608846

KEGG: hsa:126129

STRING: 9606.ENSP00000319343

UniGene: Hs.112195

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