CSF2RB Antibody

Datasheet
Code CSB-PA006047LA01HU
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Size US$299Purchase it in Cusabio online store
(only available for customers from the US)
Uniprot No. P32927
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  • Immunohistochemistry of paraffin-embedded human ovarian cancer using CSB-PA006047LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human cervical cancer using CSB-PA006047LA01HU at dilution of 1:100

  • Immunofluorescence staining of Hela cells with CSB-PA006047LA01HU at 1:66, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

  • Immunofluorescence staining of MCF-7 cells with CSB-PA006047LA01HU at 1:66, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

Immunogen Recombinant Human Cytokine receptor common subunit beta protein (492-710AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200
Relevance High affinity receptor for interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor.
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Cytokine receptor common subunit beta (CDw131) (GM-CSF/IL-3/IL-5 receptor common beta subunit) (CD antigen CD131), CSF2RB, IL3RB IL5RB
Immunogen Species Human
Protocols ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
Research Area Immunology
Target Names CSF2RB
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function High affinity receptor for interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor.
Involvement in disease Pulmonary surfactant metabolism dysfunction 5 (SMDP5)
Subcellular Location Membrane, Single-pass type I membrane protein
Protein Families Type I cytokine receptor family, Type 4 subfamily
Database Links

HGNC: 2436

OMIM: 138981

KEGG: hsa:1439

STRING: 9606.ENSP00000384053

UniGene: Hs.592192

Pathway Jak-STAT signaling pathway
Apoptosis

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