Your Good Partner in Biology Research
Your Good Partner in Biology Research
| Code | CSB-PA000024 |
| Size |
US$167Purchase it in Cusabio online store (only available for customers from the US) |
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| Have Questions? | Leave a Message or Start an on-line Chat |
| Uniprot No. | P51878 | ||||||
| Target Names | CASP5 | ||||||
| Alternative Names | Apoptosis related cysteine protease antibody; CASP-5 antibody; CASP5 antibody; CASP5_HUMAN antibody; Caspase-5 subunit p10 antibody; ICE(rel)-III antibody; ICERELIII antibody; ICH 3 antibody; ICH 3 protease antibody; Protease ICH-3 antibody; Protease TY antibody; TY antibody; TY protease antibody | ||||||
| Raised in | Rabbit | ||||||
| Species Reactivity | Human | ||||||
| Immunogen | Synthesized peptide derived from the C-terminal region of Human Caspase-5 p10. | ||||||
| Immunogen Species | Homo sapiens (Human) | ||||||
| Conjugate | Non-conjugated | ||||||
| Isotype | IgG | ||||||
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | ||||||
| Concentration | It differs from different batches. Please contact us to confirm it. | ||||||
| Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. | ||||||
| Form | Liquid | ||||||
| Tested Applications | WB, ELISA | ||||||
| Recommended Dilution |
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| Protocols | Western Blotting(WB) Protocol ELISA Protocol |
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| Troubleshooting and FAQs | Antibody FAQs | ||||||
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | ||||||
| Lead Time | Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time. |
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| Function |
Thiol protease that acts as a mediator of programmed cell death. Initiates pyroptosis, a programmed lytic cell death pathway through cleavage of Gasdermin-D (GSDMD): cleavage releases the N-terminal gasdermin moiety (Gasdermin-D, N-terminal) that binds to membranes and forms pores, triggering pyroptosis. During non-canonical inflammasome activation, cuts CGAS and may play a role in the regulation of antiviral innate immune activation.
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| Gene References into Functions |
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| Protein Families | Peptidase C14A family |
| Tissue Specificity | Expressed in barely detectable amounts in most tissues except brain, highest levels being found in lung, liver and skeletal muscle. |
| Database Links |
HGNC: 1506 OMIM: 602665 KEGG: hsa:838 STRING: 9606.ENSP00000376849 UniGene: Hs.213327 |
