Cleaved-CTSV (L114) Antibody

Datasheet

Code	CSB-PA000037
Size	US$119
	Order now
Image	Western Blot analysis of HeLa cells using Cleaved-Cathepsin L2 (L114) Polyclonal Antibody
Have Questions?	Leave a Message or Start an on-line Chat

Product Details
Related Products
Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

O60911

Target Names

CTSV

Alternative Names

CAT L2 antibody; Cathepsin L2 antibody; Cathepsin U antibody; Cathepsin V antibody; CathepsinL2 antibody; CathepsinU antibody; CathepsinV antibody; CATL 2 antibody; CATL2 antibody; CATL2_HUMAN antibody; CTS L2 antibody; CTS U antibody; CTS V antibody; CTSL 2 antibody; CTSL2 antibody; CTSU antibody; CTSV antibody; MGC125957 antibody; PRO305 antibody; UNQ268 antibody

Raised in

Rabbit

Species Reactivity

Human,Monkey

Immunogen

Synthesized peptide derived from the Internal region of Human Cathepsin L2.

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Form

Liquid

Tested Applications

WB, ELISA

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:2000
ELISA	1:20000

Protocols

Western Blotting(WB) Protocol
ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

■ Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function

Cysteine protease. May have an important role in corneal physiology.

Gene References into Functions

CTSV is involved in melanosome degradation. PMID: 29654760
exogenous CTSV inhibited Ang -induced hypertrophy in HCM cells by inhibiting PI3K/Akt/mTOR PMID: 28522343
Cathepsins V and S may serve as auxiliary diagnostic and/or prognostic markers in thymic epithelial tumors. PMID: 27771373
E2F1 directly binds to CTSL2 promoter and regulates CTSL2 gene expression. PMID: 23542171
using cathepsin V and cathepsin L as model enzymes, a series of chimeras were generated to identify noncatalytic regions that are responsible for the potent elastolytic activity of cathepsin V PMID: 24121514
Cathepsin V expression contributes to the development of dermal fibrosis and vasculopathy in systemic sclerosis. PMID: 23287360
functions of cathepsin V are controlled by N-glycosylation PMID: 22967898
Findings indicate the unique function of cathepsin V for producing enkephalin and neuropeptide Y (NPY) neuropeptides required for neurotransmission in health and neurological diseases. PMID: 22393040
CTSL2 might be involved in progression of endometrial cancer. PMID: 22452389
A proteolytically active variant of cathepsin V is localized to cell nucleus (in peri-nucleolar pattern) in thyroid carcinoma cells. PMID: 20536394
stratum corneum thiol protease is identical with the recently described cathepsin L2 protease. PMID: 12648222
Cathepsin V is involved in the degradation of invariant chain in human thymus PMID: 12925692
Cathepsin V has an elastolytic activity and is expressed in activated macrophages PMID: 15192101
Human cathepsin V compensates for murine cathepsin L in mouse epidermis and hair follicles. PMID: 15679121
propeptide was found to behave as a tight-binding inhibitor against CatV PMID: 17516850
Associated with type 1 diabetes and early-onset myasthenia gravis. PMID: 17869649
angiogenesis inhibition activity on endothelial cells caused by plasminogen processing by cathepsin V PMID: 18163891

Hide All

Subcellular Location

Lysosome.

Protein Families

Peptidase C1 family

Tissue Specificity

Predominantly expressed in the thymus and testis. Also expressed in corneal epithelium, and to a lesser extent in conjunctival epithelium and skin.

Database Links

HGNC: 2538

OMIM: 603308

KEGG: hsa:1515

STRING: 9606.ENSP00000259470

UniGene: Hs.610096

Promotions

Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Apoptosis

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

Join us with

Subscribe newsletter

Leave a message

Message

Product >> Product Name：
Product >> Code：
Name： *
Email： *
Company/Organization：
Phone：
Since emails may get flagged by spam filters occasionally, we recommend leaving your phone number as a precaution. Your information is safe with us.
Question/Comment： *
Your Region： *
I'd like to receive email newsletters from Cusabio

Yes

No
How do you know CUSABIO?

Email

Distributor

Search engine

Advertisement

Others
CAPTCHA verification：
If CAPTCHA verification fails, click to refresh the CAPTCHA and try again.

Place an order now

I. Product details

Product name *

Code *

Size *

Quantity *

Message

II. Contact details

Name *

Email address *

Company/Organization

Phone

III. Ship To

Address *

City *

State/Province *

Zip/Post code *

Country *

Attn Name *

Phone# *

IV. Bill To Same as Shipping Address