CTSV Antibody

1. CTSV is involved in melanosome degradation. PMID: 29654760
2. exogenous CTSV inhibited Ang -induced hypertrophy in HCM cells by inhibiting PI3K/Akt/mTOR PMID: 28522343
3. Cathepsins V and S may serve as auxiliary diagnostic and/or prognostic markers in thymic epithelial tumors. PMID: 27771373
4. E2F1 directly binds to CTSL2 promoter and regulates CTSL2 gene expression. PMID: 23542171
5. using cathepsin V and cathepsin L as model enzymes, a series of chimeras were generated to identify noncatalytic regions that are responsible for the potent elastolytic activity of cathepsin V PMID: 24121514
6. Cathepsin V expression contributes to the development of dermal fibrosis and vasculopathy in systemic sclerosis. PMID: 23287360
7. functions of cathepsin V are controlled by N-glycosylation PMID: 22967898
8. Findings indicate the unique function of cathepsin V for producing enkephalin and neuropeptide Y (NPY) neuropeptides required for neurotransmission in health and neurological diseases. PMID: 22393040
9. CTSL2 might be involved in progression of endometrial cancer. PMID: 22452389
10. A proteolytically active variant of cathepsin V is localized to cell nucleus (in peri-nucleolar pattern) in thyroid carcinoma cells. PMID: 20536394
11. stratum corneum thiol protease is identical with the recently described cathepsin L2 protease. PMID: 12648222
12. Cathepsin V is involved in the degradation of invariant chain in human thymus PMID: 12925692
13. Cathepsin V has an elastolytic activity and is expressed in activated macrophages PMID: 15192101
14. Human cathepsin V compensates for murine cathepsin L in mouse epidermis and hair follicles. PMID: 15679121
15. propeptide was found to behave as a tight-binding inhibitor against CatV PMID: 17516850
16. Associated with type 1 diabetes and early-onset myasthenia gravis. PMID: 17869649
17. angiogenesis inhibition activity on endothelial cells caused by plasminogen processing by cathepsin V PMID: 18163891

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HGNC: 2538

OMIM: 603308

KEGG: hsa:1515

STRING: 9606.ENSP00000259470

UniGene: Hs.610096