Cobra venom factor Antibody

Code CSB-PA856221LA01NAF
Size US$166
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  • Western Blot
    Positive WB detected in Recombinant protein
    All lanes: Cobra venom factor antibody at 3μg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    predicted band size: 45 kDa
    observed band size: 45 kDa
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Product Details

Uniprot No.
Alternative Names
antibody; Cobra venom factor antibody; CVF antibody; CVFk antibody; Complement C3 homolog) [Cleaved into: Cobra venom factor alpha chain; Cobra venom factor gamma chain; Cobra venom factor beta chain] antibody
Raised in
Rabbit
Species Reactivity
Naja kaouthia
Immunogen
Recombinant Naja kaouthia Cobra venom factor protein (733-984AA)
Immunogen Species
Naja kaouthia
Conjugate
Non-conjugated

The Cobra venom factor Antibody (Product code: CSB-PA856221LA01NAF) is Non-conjugated. For Cobra venom factor Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA856221LB01NAF Cobra venom factor Antibody, HRP conjugated ELISA
FITC CSB-PA856221LC01NAF Cobra venom factor Antibody, FITC conjugated
Biotin CSB-PA856221LD01NAF Cobra venom factor Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Complement-activating protein in cobra venom. It is a structural and functional analog of complement component C3b, the activated form of C3. It binds factor B (CFB), which is subsequently cleaved by factor D (CFD) to form the bimolecular complex CVF/Bb. CVF/Bb is a C3/C5 convertase that cleaves both complement components C3 and C5. Structurally, it resembles the C3b degradation product C3c, which is not able to form a C3/C5 convertase. Unlike C3b/Bb, CVF/Bb is a stable complex and completely resistant to the actions of complement regulatory factors H (CFH) and I (CFI). Therefore, CVF continuously activates complement resulting in the depletion of complement activity.
Subcellular Location
Secreted.
Protein Families
Venom complement C3 homolog family
Tissue Specificity
Expressed by the venom gland.
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