DAPP1 Antibody

Code CSB-PA000972
Size US$100
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  • Western Blot analysis of 293 cells using BAM32 Polyclonal Antibody
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Product Details

Uniprot No.
Target Names
DAPP1
Alternative Names
B cell adapter molecule of 32 kDa antibody; B lymphocyte adapter protein Bam32 antibody; B-cell adapter molecule of 32 kDa antibody; BAM32 antibody; DAPP1 antibody; DAPP1_HUMAN antibody; DKFZp667E0716 antibody; Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide antibody; Dual adaptor of phosphotyrosine and 3 phosphoinositides antibody; hDAPP1 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Synthesized peptide derived from Human BAM32 around the non-phosphorylation site of Y139.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, IHC, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:10000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR)-signaling downstream of PI3K.
Gene References into Functions
  1. we propose a role for Bam32 in the signaling of MHC class I molecules in professional Ag-presenting DC for the regulation of CD8(+) T cell activation. PMID: 21930970
  2. novel phosphorylation-dependent function of Bam32 in regulating Rac1 activation and actin remodeling. PMID: 15247305
  3. BAM32 works downstream of Src family protein tyrosine kinases and functions to link B cell antigen receptor signals with antigen-processing pathways in B cells. PMID: 15494510
Subcellular Location
Cytoplasm. Membrane; Peripheral membrane protein. Note=Membrane-associated after cell stimulation leading to its translocation.
Tissue Specificity
Highly expressed in placenta and lung, followed by brain, heart, kidney, liver, pancreas and skeletal muscle. Expressed by B-lymphocytes, but not T-lymphocytes or nonhematopoietic cells.
Database Links

HGNC: 16500

OMIM: 605768

KEGG: hsa:27071

STRING: 9606.ENSP00000423602

UniGene: Hs.436271

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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