B cell adapter molecule of 32 kDa antibody; B lymphocyte adapter protein Bam32 antibody; B-cell adapter molecule of 32 kDa antibody; BAM32 antibody; DAPP1 antibody; DAPP1_HUMAN antibody; DKFZp667E0716 antibody; Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide antibody; Dual adaptor of phosphotyrosine and 3 phosphoinositides antibody; hDAPP1 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human DAPP1
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
May act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR)-signaling downstream of PI3K.
Gene References into Functions
we propose a role for Bam32 in the signaling of MHC class I molecules in professional Ag-presenting DC for the regulation of CD8(+) T cell activation. PMID: 21930970
novel phosphorylation-dependent function of Bam32 in regulating Rac1 activation and actin remodeling. PMID: 15247305
BAM32 works downstream of Src family protein tyrosine kinases and functions to link B cell antigen receptor signals with antigen-processing pathways in B cells. PMID: 15494510
Subcellular Location
Cytoplasm. Membrane; Peripheral membrane protein. Note=Membrane-associated after cell stimulation leading to its translocation.
Tissue Specificity
Highly expressed in placenta and lung, followed by brain, heart, kidney, liver, pancreas and skeletal muscle. Expressed by B-lymphocytes, but not T-lymphocytes or nonhematopoietic cells.