DCN Antibody

Datasheet
Code CSB-PA006554GA01HU
Product Type Purified Rabbit Anti human PolyClonal Antibody
Size US$685
Uniprot No. P07585
Immunogen Human DCN
Raised in Rabbit
Species Reactivity Human,Mouse,Rat
Tested Applications ELISA,WB
Storage Buffer PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Purification Method Antigen Affinity purified
Isotype IgG
Alias decorin;DCN;CSCD;DSPG2;PG40;PGII;PGS2;SLRR1B ;
Immunogen Species Homo sapiens (Human)
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Target Names DCN
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Details This protein is a small cellular or pericellular matrix proteoglycan that is closely related in structure to biglycan protein. The encoded protein and biglycan are thought to be the result of a gene duplication. This protein is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly. It contains one attached glycosaminoglycan chain. This protein is capable of suppressing the growth of various tumor cell lines. There are multiple alternatively spliced transcript variants known for this gene. This gene is a candidate gene for Marfan syndrome.
HGNC 2705
RGD 61895
MGI 94872
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Function May affect the rate of fibrils formation.
Involvement in disease Corneal dystrophy, congenital stromal (CSCD)
Subcellular Location Secreted, extracellular space, extracellular matrix
Protein Families Small leucine-rich proteoglycan (SLRP) family, SLRP class I subfamily
Database Links

HGNC: 2705

OMIM: 125255

KEGG: hsa:1634

STRING: 9606.ENSP00000052754

UniGene: Hs.156316

Pathway TGF-beta signaling pathway

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