DNAJC19 Antibody

Datasheet

Code	CSB-PA853400ESR1HU
Size	US$166
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Image	Western blot All lanes: DNAJC19 antibody at 0.96µg/ml Lane 1: Mouse kidney tissue Lane 2: A549 whole cell lysate Lane 3: HL60 whole cell lysate Lane 4: Hela whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 13, 11 kDa Observed band size: 13 kDa Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA853400ESR1HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA853400ESR1HU at dilution of 1:100 Immunoprecipitating DNAJC19 in Hela whole cell lysate Lane 1: Rabbit control IgG instead of CSB-PA853400ESR1HU in Hela whole cell lysate. For western blotting, a HRP-conjugated Protein G antibody was used as the secondary antibody (1/2000) Lane 2: CSB-PA853400ESR1HU (8µg) + Hela whole cell lysate (500µg) Lane 3: Hela whole cell lysate (10µg)
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) DNAJC19 Polyclonal antibody

Uniprot No.

Q96DA6

Target Names

DNAJC19

Alternative Names

DnaJ (Hsp40) homolog; subfamily C; member 19 antibody; DnaJ homolog subfamily C member 19 antibody; DNAJC19 antibody; homolog of yeast TIM14 antibody; Mitochondrial import inner membrane translocase subunit TIM14 antibody; PAM18 antibody; TIM 14 antibody; TIM14 antibody; TIM14_HUMAN antibody; TIMM 14 antibody; TIMM14 antibody; translocase of the inner mitochondrial membrane 14 antibody; Translocase of the inner mitochondrial membrane 14; yeast homolog of antibody

Raised in

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Recombinant Human Mitochondrial import inner membrane translocase subunit TIM14 protein (1-116AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Tested Applications

ELISA, WB, IHC, IP

Recommended Dilution

Application	Recommended Dilution
WB	1:1000-1:5000
IHC	1:20-1:200
IP	1:200-1:2000

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunoprecipitation (IP) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Mitochondrial co-chaperone which forms a complex with prohibitins to regulate cardiolipin remodeling. May be a component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. May act as a co-chaperone that stimulate the ATP-dependent activity.

Gene References into Functions

Both DnaJC15 and DnaJC19 formed two distinct subcomplexes with Magmas at the import channel. PMID: 27330077
The loss of DNAJC19/PHB complexes affects cardiolipin acylation and leads to the accumulation of cardiolipin species with altered acyl chains. PMID: 24856930
A report of a new mutation in the human DNAJC19 gene that causes early onset dilated cardiomyopathy syndrome in two brothers of Finnish origin. PMID: 22797137
The association of dilated cardiomyopathy with ataxia (DCMA) syndrome with a segment of 3q26.33 and the identification of a splice mutation in a novel gene DNAJC19 in DCMA patients. PMID: 16055927
Dilated cardiomyopathy caused by homozygous mutations in a novel gene, DNAJC19, presumed to play a role in importation of mitochondrial proteins. PMID: 17244376

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Involvement in disease

3-methylglutaconic aciduria 5 (MGA5)

Subcellular Location

Mitochondrion inner membrane; Single-pass membrane protein; Matrix side.

Protein Families

TIM14 family

Tissue Specificity

Ubiquitously expressed.

Database Links

HGNC: 30528

OMIM: 608977

KEGG: hsa:131118

STRING: 9606.ENSP00000372005

UniGene: Hs.230601

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Protein Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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