E7 Antibody

Code CSB-PA361948LA01HMN
Size US$166
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Product Details

Full Product Name
Rabbit anti-Human papillomavirus type 18 E7 Polyclonal antibody
Uniprot No.
Target Names
E7
Alternative Names
E7Protein E7 antibody
Raised in
Rabbit
Species Reactivity
Human papillomavirus type 18
Immunogen
Recombinant Human papillomavirus type 18 Protein E7 protein (1-105AA)
Immunogen Species
Human papillomavirus type 18
Conjugate
Non-conjugated

The E7 Antibody (Product code: CSB-PA361948LA01HMN) is Non-conjugated. For E7 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA361948LB01HMN E7 Antibody, HRP conjugated ELISA
FITC CSB-PA361948LC01HMN E7 Antibody, FITC conjugated
Biotin CSB-PA361948LD01HMN E7 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. E7 protein has both transforming and trans-activating activities. Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation. Plays also a role in the inhibition of both antiviral and antiproliferative functions of host interferon alpha. Interaction with host TMEM173/STING impairs the ability of TMEM173/STING to sense cytosolic DNA and promote the production of type I interferon (IFN-alpha and IFN-beta).
Subcellular Location
Host cytoplasm. Host nucleus.
Protein Families
Papillomaviridae E7 protein family
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