ERGIC2 Antibody

Code CSB-PA857020ESR2HU
Size US$166
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  • Western blot
    All lanes: Endoplasmic reticulum-Golgi intermediate compartment protein 2 antibody at 4μg/ml
    Lane 1: HepG2 whole cell lysate
    Lane 2: Jurkat whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 43 kDa
    Observed band size: 43 kDa

  • Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA857020ESR2HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ERGIC2 Polyclonal antibody
Uniprot No.
Target Names
ERGIC2
Alternative Names
ERGIC2; ERV41; PTX1; CDA14; Endoplasmic reticulum-Golgi intermediate compartment protein 2
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Endoplasmic reticulum-Golgi intermediate compartment protein 2 protein (55-310AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Possible role in transport between endoplasmic reticulum and Golgi.
Gene References into Functions
  1. A variant of ERGIC2 with four coding bases deleted has an abrogated function as a transport shuttle, but does continue to upregulate the heme oxygenase 1 gene, suggesting that it may be involved in the oxidative stress pathway. PMID: 24303950
  2. may play an important role in the growth and tumorigenicity of PC-3 prostate tumor cells PMID: 12932305
  3. ERGIC-32 functions as a modulator of the hErv41-hErv46 complex by stabilizing hErv46 PMID: 15308636
  4. Ectopic expression of a partial sequence of PTX1 (Met84 - Leu225) as a VP22-fusion protein in prostate cancer cell line, PC-3, induced cellular senescence. PMID: 16989575
  5. CDA14 participated in the elongation factor 1alpha regulated mechanisms PMID: 17980171

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Subcellular Location
Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Cytoplasm. Nucleus.
Protein Families
ERGIC family
Tissue Specificity
Ubiquitously expressed.
Database Links

HGNC: 30208

OMIM: 612236

KEGG: hsa:51290

STRING: 9606.ENSP00000353270

UniGene: Hs.339453

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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