ERGIC2 Antibody

Code CSB-PA857020ESR2HU
Size US$166
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  • Western blot
    All lanes: Endoplasmic reticulum-Golgi intermediate compartment protein 2 antibody at 4μg/ml
    Lane 1: HepG2 whole cell lysate
    Lane 2: Jurkat whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 43 kDa
    Observed band size: 43 kDa

  • Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA857020ESR2HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ERGIC2 Polyclonal antibody
Uniprot No.
Target Names
ERGIC2
Alternative Names
ERGIC2; ERV41; PTX1; CDA14; Endoplasmic reticulum-Golgi intermediate compartment protein 2
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Endoplasmic reticulum-Golgi intermediate compartment protein 2 protein (55-310AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Possible role in transport between endoplasmic reticulum and Golgi.
Gene References into Functions
  1. A variant of ERGIC2 with four coding bases deleted has an abrogated function as a transport shuttle, but does continue to upregulate the heme oxygenase 1 gene, suggesting that it may be involved in the oxidative stress pathway. PMID: 24303950
  2. may play an important role in the growth and tumorigenicity of PC-3 prostate tumor cells PMID: 12932305
  3. ERGIC-32 functions as a modulator of the hErv41-hErv46 complex by stabilizing hErv46 PMID: 15308636
  4. Ectopic expression of a partial sequence of PTX1 (Met84 - Leu225) as a VP22-fusion protein in prostate cancer cell line, PC-3, induced cellular senescence. PMID: 16989575
  5. CDA14 participated in the elongation factor 1alpha regulated mechanisms PMID: 17980171

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Subcellular Location
Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Cytoplasm. Nucleus.
Protein Families
ERGIC family
Tissue Specificity
Ubiquitously expressed.
Database Links

HGNC: 30208

OMIM: 612236

KEGG: hsa:51290

STRING: 9606.ENSP00000353270

UniGene: Hs.339453

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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