FBXO2 Antibody

1. Fbs1 GYR variant may be employed for substantially unbiased enrichment of N-linked glycopeptides from human serum PMID: 28534482
2. These results suggest that the FBXO2 variant rs9614 C allele may decrease the Parkinson Disease risk in mainland Han Chinese and may be a biomarker for PD. PMID: 28341977
3. summary, our findings suggest that FBXO2-regulated EMT led to carcinogenicity in gastric cancer and may be a novel target in the diagnosis and treatment of gastric cancer. PMID: 29269301
4. Structural analysis of a function-associated loop mutant of the substrate-recognition domain of Fbs1 ubiquitin ligase has been presented. PMID: 27487926
5. This study provides new knowledge of the CFTR biosynthetic pathway. It suggests that SYVN1 and FBXO2 represent two distinct multiprotein complexes that may degrade DeltaF508-CFTR in airway epithelia and identifies a new role for NEDD8 in regulating DeltaF508-CFTR ubiquitination. PMID: 27756846
6. Although the overall structure of FBG3 is similar to that of Fbs1, the residues that form the Fbs1 carbohydrate-binding pocket failed to be superposed with the corresponding residues of FBG3. PMID: 26460611
7. FBG1 degrades A1AT-Z through a Beclin1-dependent arm of autophagy. PMID: 26295339
8. FBG1 is unique among known F-box proteins in that it contains a non-canonical D-Box within F-box domain, required for the growth arrest. PMID: 21135578
9. interaction of the HSV-1 UL9 protein with NFB42 results in its polyubiquitination and subsequent degradation by the 26S proteasome PMID: 12904574

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HGNC: 13581

OMIM: 607112

KEGG: hsa:26232

STRING: 9606.ENSP00000346240

UniGene: Hs.132753