F-box only protein 2is a protein in humans that is encoded by FBXO2 gene. Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Involved in the endoplasmic reticulum-associated degradation pathway (ERAD) for misfolded lumenal proteins by recognizing and binding sugar chains on unfolded glycoproteins that are retrotranslocated into the cytosol and promoting their ubiquitination and subsequent degradation. Prevents formation of cytosolic aggregates of unfolded glycoproteins that have been retrotranslocated into the cytosol. Able to recognize and bind denatured glycoproteins, preferentially those of the high-mannose type (By similarity).
The following FBXO2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
FBXO2 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA008487GA01HU | FBXO2 Antibody |
Human,Mouse,Rat | ELISA,IHC |
CSB-PA892326ESR1HU | FBXO2 Antibody |
Human | ELISA, IHC |
FBXO2 Proteins for Bos taurus (Bovine)
Code | Product Name | Source |
---|---|---|
CSB-YP623160BO CSB-EP623160BO CSB-BP623160BO CSB-MP623160BO CSB-EP623160BO-B |
Recombinant Bovine F-box only protein 2 (FBXO2) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FBXO2 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP802228MO CSB-EP802228MO CSB-BP802228MO CSB-MP802228MO CSB-EP802228MO-B |
Recombinant Mouse F-box only protein 2 (Fbxo2) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FBXO2 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP892326HU CSB-BP892326HU CSB-MP892326HU CSB-EP892326HU-B |
Recombinant Human F-box only protein 2 (FBXO2) |
Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP892326HU | Recombinant Human F-box only protein 2 (FBXO2) |
E.coli |