FCRL6 Antibody

Code CSB-PA718779ESR2HU
Size US$166
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  • Western blot
    All lanes: FCRL6 antibody at 1.29μg/ml
    Lane 1: Hela whole cell lysate
    Lane 2: A549 whole cell lysate
    Lane 3: Jurkat whole cell lysate
    Lane 4: HepG2 whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 48, 46, 44, 35 kDa
    Observed band size: 48 kDa

  • Immunohistochemistry of paraffin-embedded human ovarian cancer using CSB-PA718779ESR2HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA718779ESR2HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) FCRL6 Polyclonal antibody
Uniprot No.
Target Names
Alternative Names
Fc receptor homolog 6 antibody; Fc receptor-like 6 antibody; Fc receptor-like protein 6 antibody; Fc receptor-like protein 7 antibody; FcR-like protein 6 antibody; FcRH6 antibody; FcRL6 antibody; FCRL6_HUMAN antibody; FLJ16056 antibody; IFGP6 antibody; IgSF type I transmembrane receptor antibody; leukocyte receptor antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Fc receptor-like protein 6 protein (20-307AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Acts as a MHC class II receptor. When stimulated on its own, does not play a role in cytokine production or the release of cytotoxic granules by NK cells and cytotoxic CD8(+) T cells. Does not act as an Fc receptor.
Gene References into Functions
  1. Human FCRL6 receptor, selectively expressed by cytotoxic T and natural killer (NK) cells, directly binds the major histocompatibility complex (MHC) class II molecule HLA-DR. PMID: 20519654
  2. FCRL6 is a distinct indicator of cytotoxic effector lymphocytes that is upregulated in diseases characterized by chronic immune stimulation. PMID: 18991291
Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Tissue Specificity
Expressed by cytolytic cells including NK cells, effector and effector-memory CD8(+) T-cells, and a subset of NKT cells (at protein level). Also expressed in gamma delta T cells and in a rare subset of effector CD4(+) T-cells (at protein level). Expressed
Database Links

HGNC: 31910

OMIM: 613562

KEGG: hsa:343413

UniGene: Hs.196955

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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