FCRL6 Antibody

Code CSB-PA718779ESR2HU
Size US$166
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  • Western blot
    All lanes: FCRL6 antibody at 1.29μg/ml
    Lane 1: Hela whole cell lysate
    Lane 2: A549 whole cell lysate
    Lane 3: Jurkat whole cell lysate
    Lane 4: HepG2 whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 48, 46, 44, 35 kDa
    Observed band size: 48 kDa

  • Immunohistochemistry of paraffin-embedded human ovarian cancer using CSB-PA718779ESR2HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA718779ESR2HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) FCRL6 Polyclonal antibody
Uniprot No.
Target Names
FCRL6
Alternative Names
Fc receptor homolog 6 antibody; Fc receptor-like 6 antibody; Fc receptor-like protein 6 antibody; Fc receptor-like protein 7 antibody; FcR-like protein 6 antibody; FcRH6 antibody; FcRL6 antibody; FCRL6_HUMAN antibody; FLJ16056 antibody; IFGP6 antibody; IgSF type I transmembrane receptor antibody; leukocyte receptor antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Fc receptor-like protein 6 protein (20-307AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Acts as a MHC class II receptor. When stimulated on its own, does not play a role in cytokine production or the release of cytotoxic granules by NK cells and cytotoxic CD8(+) T cells. Does not act as an Fc receptor.
Gene References into Functions
  1. Human FCRL6 receptor, selectively expressed by cytotoxic T and natural killer (NK) cells, directly binds the major histocompatibility complex (MHC) class II molecule HLA-DR. PMID: 20519654
  2. FCRL6 is a distinct indicator of cytotoxic effector lymphocytes that is upregulated in diseases characterized by chronic immune stimulation. PMID: 18991291
Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Tissue Specificity
Expressed by cytolytic cells including NK cells, effector and effector-memory CD8(+) T-cells, and a subset of NKT cells (at protein level). Also expressed in gamma delta T cells and in a rare subset of effector CD4(+) T-cells (at protein level). Expressed
Database Links

HGNC: 31910

OMIM: 613562

KEGG: hsa:343413

UniGene: Hs.196955

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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