FIZ1 Antibody

Code CSB-PA839415LA01HU
Size US$166
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Image
  • Western Blot
    Positive WB detected in: 293 whole cell lysate
    All lanes: FIZ1 antibody at 4.5µg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 52 kDa
    Observed band size: 52 kDa

  • IHC image of CSB-PA839415LA01HU diluted at 1:300 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) FIZ1 Polyclonal antibody
Uniprot No.
Target Names
FIZ1
Alternative Names
FIZ1 antibody; ZNF798Flt3-interacting zinc finger protein 1 antibody; Zinc finger protein 798 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Flt3-interacting zinc finger protein 1 protein (252-410AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The FIZ1 Antibody (Product code: CSB-PA839415LA01HU) is Non-conjugated. For FIZ1 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA839415LB01HU FIZ1 Antibody, HRP conjugated ELISA
FITC CSB-PA839415LC01HU FIZ1 Antibody, FITC conjugated
Biotin CSB-PA839415LD01HU FIZ1 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
IHC 1:200-1:500
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May be a transcriptional repressor of NRL function in photoreceptors. Does not repress CRX-mediated transactivation.
Gene References into Functions
  1. Signal transducer/transcription factor FIZ1 regulated signaling pathways are implicated in regulation of the balance between proliferation and differentiation in keratinocytes. PMID: 24956037
  2. Activators of the Rhodopsin gene are present before activation of the gene. FIZ1 expression rises at this time and it can synergize with NRL and CRX at the Rho and PDE6B promoters. FIZ1 may syncronize the onset of maturation related gene expression. PMID: 17141759
  3. Homologous to mouse and bovine Fiz1 (flt-3 interacting zinc finger). Interacts with NRL (neural retina leucine zipper). Antibody detects protein in human, mouse, bovine retina. Possible role for Fiz1 as a transcriptional repressor. PMID: 12566383
Subcellular Location
Cytoplasm. Nucleus.
Tissue Specificity
Widely expressed.
Database Links

HGNC: 25917

OMIM: 609133

KEGG: hsa:84922

STRING: 9606.ENSP00000221665

UniGene: Hs.515617

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