FIZ1 Antibody

Code CSB-PA008685GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
FIZ1
Alternative Names
FIZ1 antibody; ZNF798Flt3-interacting zinc finger protein 1 antibody; Zinc finger protein 798 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human domain-II-of-FIZ1
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May be a transcriptional repressor of NRL function in photoreceptors. Does not repress CRX-mediated transactivation.
Gene References into Functions
  1. Signal transducer/transcription factor FIZ1 regulated signaling pathways are implicated in regulation of the balance between proliferation and differentiation in keratinocytes. PMID: 24956037
  2. Activators of the Rhodopsin gene are present before activation of the gene. FIZ1 expression rises at this time and it can synergize with NRL and CRX at the Rho and PDE6B promoters. FIZ1 may syncronize the onset of maturation related gene expression. PMID: 17141759
  3. Homologous to mouse and bovine Fiz1 (flt-3 interacting zinc finger). Interacts with NRL (neural retina leucine zipper). Antibody detects protein in human, mouse, bovine retina. Possible role for Fiz1 as a transcriptional repressor. PMID: 12566383
Subcellular Location
Cytoplasm. Nucleus.
Tissue Specificity
Widely expressed.
Database Links

HGNC: 25917

OMIM: 609133

KEGG: hsa:84922

STRING: 9606.ENSP00000221665

UniGene: Hs.515617

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