IL13RA1 Antibody, FITC conjugated

Datasheet
Code CSB-PA011591LC01HU
Size US$299
Uniprot No. P78552
Protocols ELISA Protocol
Immunogen Recombinant Human Interleukin-13 receptor subunit alpha-1 protein (22-234AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity.
Form Liquid
Conjugate FITC
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method Antigen Affinity Purified
Isotype IgG
Clonality Polyclonal
Alias Interleukin-13 receptor subunit alpha-1 (IL-13 receptor subunit alpha-1) (IL-13R subunit alpha-1) (IL-13R-alpha-1) (IL-13RA1) (Cancer/testis antigen 19) (CT19) (CD antigen CD213a1), IL13RA1, IL13R IL13RA
Immunogen Species Homo sapiens (Human)
Research Area Immunology
Target Names IL13RA1
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity.
Subcellular Location Membrane, Single-pass type I membrane protein
Protein Families Type I cytokine receptor family, Type 5 subfamily
Tissue Specificity Ubiquitous. Highest levels in heart, liver, skeletal muscle and ovary; lowest levels in brain, lung and kidney. Also found in B-cells, T-cells and endothelial cells.
Database Links

HGNC: 5974

OMIM: 300119

KEGG: hsa:3597

STRING: 9606.ENSP00000360730

UniGene: Hs.496646

Pathway Jak-STAT signaling pathway

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