Recombinant Human Interleukin-13 receptor subunit alpha-1(IL13RA1)

Code CSB-CF011591HU
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. P78552
Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Species Homo sapiens (Human)
Source in vitro E.coli expression system
Gene Names IL13RA1
Protein Names Recommended name: Interleukin-13 receptor subunit alpha-1 Short name= IL-13 receptor subunit alpha-1 Short name= IL-13R subunit alpha-1 Short name= IL-13R-alpha-1 Short name= IL-13RA1 Alternative name(s): Cancer/testis antigen 19 Short n
Expression Region 22-427
Tag Info N-terminal 10xHis-tagged
Protein Description Full Length of Mature Protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity.
Subcellular Location Membrane, Single-pass type I membrane protein
Protein Families Type I cytokine receptor family, Type 5 subfamily
Tissue Specificity Ubiquitous. Highest levels in heart, liver, skeletal muscle and ovary; lowest levels in brain, lung and kidney. Also found in B-cells, T-cells and endothelial cells.
Database Links

HGNC: 5974

OMIM: 300119

KEGG: hsa:3597

STRING: 9606.ENSP00000360730

UniGene: Hs.496646

Pathway Jak-STAT signaling pathway

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