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Your Good Partner in Biology Research
| Code | CSB-AP004571HU |
| Product Type | Interleukin |
| Size |
$65Purchase it in Cusabio online store (Shop online in the US. Customers outside the US, please order from local distributors.) |
| Uniprot No. | P78552 |
| Image |
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| Storage Buffer | Lyophilized from a 0.2 μm filtered 1xPBS, pH 7.4 |
| Alias | Interleukin-13 receptor subunit alpha-1; IL-13 receptor subunit alpha-1; IL-13R subunit alpha-1; IL-13R-alpha-1; IL-13RA1; Cancer/testis antigen 19; CT19; CD213a1; IL13RA1; IL13R; IL13RA |
| Species | Homo sapiens (Human) |
| Biological_Activity | The ED50 as determined by its ability to inhibit IL-13-dependent proliferation of TF?1 human erythroleukemic cells is less than 30 ng/ml. |
| Purity | Greater than 95% as determined by SDS-PAGE. |
| Endotoxin | Less than 1.0 EU/μg as determined by LAL method. |
| Sequence | GGGGAAPTETQPPVTNLSVSVENLCTVIWTWNPPEGASSNCSLWYFSHFGDKQDKKIAPETRRSIEVPLNERICLQVGSQCSTNESEKPSILVEKCISPPEGDPESAVTELQCIWHNLSYMKCSWLPGRNTSPDTNYTLYYWHRSLEKIHQCENIFREGQYFGCSFDLTKVKDSSFEQHSVQIMVKDNAGKIKPSFNIVPLTSRVKPDPPHIKNLSFHNDDLYVQWENPQNFISRCLFYEVEVNNSQTETHNVFYVQEAKCENPEFERNVENTSCFMVPGVLPDTLNTVRIRVKTNKLCYEDDKLWSNWSQEMSIGKKRNST |
| Research Area | Immunology |
| Source | Mammalian cell |
| Gene Names | IL13RA1 |
| Expression Region | 22-343aa |
| Tag Info | C-terminal 6xHis-tagged |
| Mol. Weight | 37.7 kDa |
| Protein Description | Extracellular Domain |
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| Function | Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity. |
| Subcellular Location | Membrane, Single-pass type I membrane protein |
| Protein Families | Type I cytokine receptor family, Type 5 subfamily |
| Tissue Specificity | Ubiquitous. Highest levels in heart, liver, skeletal muscle and ovary; lowest levels in brain, lung and kidney. Also found in B-cells, T-cells and endothelial cells. |
| Database Links |
HGNC: 5974 OMIM: 300119 KEGG: hsa:3597 STRING: 9606.ENSP00000360730 UniGene: Hs.496646 |
| Pathway | Jak-STAT signaling pathway |
IL13RA1 Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA011591LA01HU | IL13RA1 Antibody | Human | ELISA, IHC, IF |
| CSB-PA011591LB01HU | IL13RA1 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA011591LC01HU | IL13RA1 Antibody, FITC conjugated | Human | ELISA |
| CSB-PA011591LD01HU | IL13RA1 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA003019 | IL13RA1 Antibody | Human,Mouse,Rat | WB,IHC,IF,ELISA |
| CSB-PA009595 | Phospho-IL13RA1 (Y405) Antibody | Human,Mouse,Rat | WB,IF,ELISA |
| CSB-PA058807 | IL13RA1 Antibody | Human | ELISA,IHC |
IL13RA1 Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-CF011591HU | Recombinant Human Interleukin-13 receptor subunit alpha-1(IL13RA1) | in vitro E.coli expression system |
| CSB-YP011591HU1 CSB-EP011591HU1 CSB-BP011591HU1 CSB-MP011591HU1 |
Recombinant Human Interleukin-13 receptor subunit alpha-1(IL13RA1),partial | Yeast E.coli Baculovirus Mammalian cell |
IL13RA1 ELISA Kit for Homo sapiens (Human)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-EL011591HU | Human Interleukin-13 receptor subunit alpha-1(IL13RA1) ELISA kit | Request Information |
Recombinant Human Ras-related protein Rab-11A(RAB11A)
Express system: E.coli
Species: Homo sapiens (Human)
Recombinant Human 60S acidic ribosomal protein P2(RPLP2)
Express system: E.coli
Species: Homo sapiens (Human)
Recombinant Human Alcohol dehydrogenase 4(ADH4)
Express system: E.coli
Species: Homo sapiens (Human)
Recombinant Human Dopamine beta-hydroxylase(DBH),partial,Yeast
Express system: Yeast
Species: Homo sapiens (Human)
Recombinant Human Cancer/testis antigen 2(CTAG2)
Express system: E.coli
Species: Homo sapiens (Human)
Recombinant Human TGFB1-induced anti-apoptotic factor 1(TIAF1)
Express system: E.coli
Species: Homo sapiens (Human)
