CD47|Proteinase K|EGFR|BCMA|PD-L1|CD276|ACE2|TMPRSS2|Exosome Isolation Kits
Code | CSB-AP004571HU |
Size |
US$1411Purchase it in Cusabio online store (only available for customers from the US) |
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Purity | Greater than 95% as determined by SDS-PAGE. |
Endotoxin | Less than 1.0 EU/μg as determined by LAL method. |
Activity | The ED50 as determined by its ability to inhibit IL-13-dependent proliferation of TF?1 human erythroleukemic cells is less than 30 ng/ml. |
Target Names | IL13RA1 |
Uniprot No. | P78552 |
Research Area | Immunology |
Alternative Names | bB128O4.2.1 (interleukin 13 receptor; alpha 1); Cancer/testis antigen 19; CD213a1; CD213A1 Antigen; CT 19; CT19; I13R1_HUMAN; IL 13 receptor subunit alpha 1; IL 13R alpha 1; IL 13R subunit alpha 1; IL 13Ra ; IL 13RA1; IL-13 receptor subunit alpha-1; IL-13R subunit alpha-1; IL-13R-alpha-1; IL-13RA1; IL13 receptor alpha 1 chain; IL13R ; IL13RA ; Il13ra1; Interleukin 13 receptor alpha 1 ; Interleukin 13 receptor alpha 1 chain; interleukin 13 receptor subunit alpha 1; Interleukin-13 receptor subunit alpha-1; NR 4; NR4 |
Species | Homo sapiens (Human) |
Source | Mammalian cell |
Expression Region | 22-343aa |
Complete Sequence | GGGGAAPTETQPPVTNLSVSVENLCTVIWTWNPPEGASSNCSLWYFSHFGDKQDKKIAPETRRSIEVPLNERICLQVGSQCSTNESEKPSILVEKCISPPEGDPESAVTELQCIWHNLSYMKCSWLPGRNTSPDTNYTLYYWHRSLEKIHQCENIFREGQYFGCSFDLTKVKDSSFEQHSVQIMVKDNAGKIKPSFNIVPLTSRVKPDPPHIKNLSFHNDDLYVQWENPQNFISRCLFYEVEVNNSQTETHNVFYVQEAKCENPEFERNVENTSCFMVPGVLPDTLNTVRIRVKTNKLCYEDDKLWSNWSQEMSIGKKRNST |
Mol. Weight | 37.7 kDa |
Protein Length | Extracellular Domain |
Tag Info |
C-terminal 6xHis-tagged |
Form | Lyophilized powder |
Buffer | Lyophilized from a 0.2 μm filtered 1xPBS, pH 7.4 |
Reconstitution | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference. |
Troubleshooting and FAQs |
Protein FAQs |
Storage Condition | Store at -20°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
Shelf Life | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. |
Lead Time | Basically, we can dispatch the products out in 5-10 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time. |
Notes | Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week. |
Datasheet & COA | Please contact us to get it. |
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Function | Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity. |
Gene References into Functions |
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Subcellular Location | Membrane, Single-pass type I membrane protein |
Protein Families | Type I cytokine receptor family, Type 5 subfamily |
Tissue Specificity | Ubiquitous. Highest levels in heart, liver, skeletal muscle and ovary; lowest levels in brain, lung and kidney. Also found in B-cells, T-cells and endothelial cells. |
Database Links |
HGNC: 5974 OMIM: 300119 KEGG: hsa:3597 STRING: 9606.ENSP00000360730 UniGene: Hs.496646 |