IL20RB Antibody

Datasheet

Code	CSB-PA003026
Size	US$119
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Image	Western Blot analysis of HeLa cells using IL-20Rβ Polyclonal Antibody
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Product Details
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Target Background

Product Details

Uniprot No.

Q6UXL0

Target Names

IL20RB

Alternative Names

DIRS1 antibody; Fibronectin type III domain containing 6 antibody; FNDC6 antibody; I20RB_HUMAN antibody; IL 20R beta antibody; IL 20R2 antibody; IL-20 receptor subunit beta antibody; IL-20R-beta antibody; IL-20R2 antibody; IL-20RB antibody; IL20RB antibody; Interleukin 20 receptor beta antibody; Interleukin 20 receptor beta chain precursor antibody; Interleukin 20 receptor II antibody; Interleukin-20 receptor subunit beta antibody; MGC34923 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse

Immunogen

Synthesized peptide derived from the Internal region of Human IL-20Rβ.

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Form

Liquid

Tested Applications

WB, IHC, ELISA

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:2000
IHC	1:100-1:300
ELISA	1:20000

Protocols

Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL22RA1/IL20RB dimer is a receptor for IL20 and IL24.

Gene References into Functions

Trabecular meshwork cells express IL-20 receptors; Mutation of the T104 residue in IL-20R2 leads to a reduction in STAT3 phosphorylation as well as decreased matrix metalloproteinase activity PMID: 24455976
The crystal structure of the IL-20/IL-20R1/IL-20R2 complex reveals how type I and II complexes discriminate cognate from noncognate ligands PMID: 22802649
The hypotheses that genetic variations of the IL-20-RI influence susceptibility to psoriasis and single nucleotide polymorphisms (SNPs) in the IL20RA and IL20RB genes in psoriasis patients were investigated. PMID: 18480827

Subcellular Location

Membrane; Single-pass type I membrane protein.

Protein Families

Type II cytokine receptor family

Tissue Specificity

Widely expressed with highest levels in skin and testis. Highly expressed in psoriatic skin.

Database Links

HGNC: 6004

OMIM: 605621

KEGG: hsa:53833

STRING: 9606.ENSP00000328133

UniGene: Hs.61232

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Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Jak-STAT signaling pathway

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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