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Product Name:

IL7R Antibody

Product Type : Polyclonal Antibody
Code : CSB-PA011670ESR2HU
Size : US$167
Uniprot NO. : P16871
Storage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Image :
  • Immunohistochemistry of paraffin-embedded human skin using CSB-PA011670ESR2HU at dilution 1:100
  • Immunohistochemistry of paraffin-embedded human rectal cancer using CSB-PA011670ESR2HU at dilution 1:100
Immunogen : Recombinant human Interleukin-7 receptor subunit alpha protein (21-239AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA,IHC;Recommended dilution:IHC:1:20-1:200
Relevance : Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP).
Form : Liquid
Conjugate : Non-conjugated
Storage Buffer : PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification method : Antigen Affinity Purified
Isotype : IgG
Clonality : Polyclonal
Alias : Interleukin-7 receptor subunit alpha,IL-7 receptor subunit alpha,IL-7R subunit alpha,IL-7R-alpha,IL-7RA,CDw127,IL7R
Species : Human
Target details : This protein is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in the V(D)J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID).
HGNC : 6024
RGD : 1309776
MGI : 96562
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