ITGB5 Antibody

Datasheet
Code CSB-PA575292
Product Type Polyclonal Antibody
Size US$297
Uniprot No. P18084
Image
  • Western blot analysis of extracts from COS7 cells, using Integrin β5 antibody.
  • Western blot analysis of extracts from JK cells (Lane 2) and cos-7 cells (Lane 3), using Integrin β5 antiobdy. The lane on the left is treated with synthesized peptide.
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunogen Synthesized peptide derived from Human Integrin β5.
Raised in Rabbit
Species Reactivity Human,Mouse,Rat
Specificity The antibody detects endogenous levels of total Integrin β5 protein.
Tested Applications ELISA,WB;WB:1:500-1:3000
Relevance Integrin alpha-V/beta-5 is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand.

Hongquan Zhang, J. Cell Biol., Sep 2002; 158: 1287.
TJ Wickham, J. Cell Biol., Oct 1994; 127: 257.
BE Vogel, J. Cell Biol., Apr 1993; 121: 461.
JW Smith, J. Biol. Chem., Jul 1990; 265: 11008 - 11013.
Form Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality Polyclonal
Alias INTEGRIN BETA-5; ITGB5;
Immunogen Species Homo sapiens (Human)
Target Names ITGB5
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Integrin alpha-V/beta-5 (ITGAV
Subcellular Location Membrane, Single-pass type I membrane protein
Protein Families Integrin beta chain family
Database Links

HGNC: 6160

OMIM: 147561

KEGG: hsa:3693

STRING: 9606.ENSP00000296181

UniGene: Hs.13155

Pathway PI3K-Akt signaling pathway
Focal adhesion
Regulation of actin cytoskeleton

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