KLRK1 Antibody, FITC conjugated

Code CSB-PA012474LC01HU
Size US$299
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Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) KLRK1 Polyclonal antibody
Uniprot No. P26718
Target Names KLRK1
Alternative Names CD314 antibody; CD314 antigen antibody; D12S2489E antibody; Killer cell lectin like receptor subfamily K member 1 antibody; Killer cell lectin-like receptor subfamily K member 1 antibody; KLR antibody; KLRC4 KLRK1 readthrough antibody; KLRK1 antibody; NK cell receptor D antibody; NK lectin-like receptor antibody; NKG2 D activating NK receptor antibody; NKG2 D type II integral membrane protein antibody; NKG2-D antibody; NKG2-D type II integral membrane protein antibody; NKG2-D-activating NK receptor antibody; Nkg2d antibody; NKG2D_HUMAN antibody; NKLLR antibody; NKR P2 antibody; Nkrp2 antibody
Raised in Rabbit
Species Reactivity Human
Immunogen Recombinant Human NKG2-D type II integral membrane protein (73-216AA)
Immunogen Species Homo sapiens (Human)
Conjugate FITC
Clonality Polyclonal
Isotype IgG
Purification Method >95%, Protein G purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form Liquid
Tested Applications ELISA
Protocols ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Target Data

Function Function as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress-inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells. Provides both stimulatory and costimulatory innate immune responses on activated killer (NK) cells, leading to cytotoxic activity. Acts as a costimulatory receptor for T-cell receptor (TCR) in CD8(+) T-cell-mediated adaptive immune responses by amplifying T-cell activation. Stimulates perforin-mediated elimination of ligand-expressing tumor cells. Signaling involves calcium influx, culminating in the expression of TNF-alpha. Participates in NK cell-mediated bone marrow graft rejection. May play a regulatory role in differentiation and survival of NK cells. Binds to ligands belonging to various subfamilies of MHC class I-related glycoproteins including MICA, MICB, RAET1E, RAET1G, RAET1L/ULBP6, ULBP1, ULBP2, ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4.
Subcellular Location Cell membrane, Single-pass type II membrane protein
Tissue Specificity Expressed in natural killer (NK) cells, CD8(+) alpha-beta and gamma-delta T-cells. Expressed on essentially all CD56+CD3- NK cells from freshly isolated PBMC. Expressed in interferon-producing killer dendritic cells (IKDCs).
Database Links

HGNC: 18788

OMIM: 611817

KEGG: hsa:100528032

STRING: 9606.ENSP00000240618

UniGene: Hs.387787

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