LILRB2 Antibody, FITC conjugated

Code CSB-PA013000LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) LILRB2 Polyclonal antibody
Uniprot No.
Target Names
LILRB2
Alternative Names
CD85 antigen-like family member D antibody; CD85d antibody; CD85d antigen antibody; ILT 4 antibody; ILT-4 antibody; ILT4 antibody; Immunoglobulin like transcript 4 antibody; Immunoglobulin-like transcript 4 antibody; Leukocyte immunoglobulin like receptor 2 antibody; Leukocyte immunoglobulin like receptor subfamily B member 2 antibody; Leukocyte immunoglobulin-like receptor 2 antibody; Leukocyte immunoglobulin-like receptor subfamily B member 2 antibody; Leukocyte immunoglobulin-like receptor; subfamily B (with TM and ITIM domains); member 2 antibody; LILRA6 antibody; LILRB2 antibody; LIR 2 antibody; LIR-2 antibody; LIR2 antibody; LIRb antibody; LIRB2_HUMAN antibody; MIR 10 antibody; MIR-10 antibody; MIR10 antibody; Monocyte/macrophage immunoglobulin like receptor 10 antibody; Monocyte/macrophage immunoglobulin-like receptor 10 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Leukocyte immunoglobulin-like receptor subfamily B member 2 protein (406-563AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles. Involved in the down-regulation of the immune response and the development of tolerance. Recognizes HLA-G in complex with B2M/beta-2 microglobulin and a nonamer self-peptide (peptide-bound HLA-G-B2M) triggering differentiation of type 1 regulatory T cells and myeloid-derived suppressor cells, both of which actively maintain maternal-fetal tolerance. Competes with CD8A for binding to class I MHC antigens. Inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.
Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Tissue Specificity
Expressed in monocytes and at lower levels in myeloid and plasmacytoid dendritic cells. Expressed in tolerogenic IL10-producing dendritic cells. Expressed in myeloid-derived suppressor cells during pregnancy. Detected at low levels in natural killer (NK)
Database Links

HGNC: 6606

OMIM: 604815

STRING: 9606.ENSP00000375629

UniGene: Hs.655652

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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