LILRB2 Antibody

Datasheet

Code	CSB-PA006212
Size	US$119
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Image	Western Blot analysis of HeLa cells using CD85d Polyclonal Antibody
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

Q8N423

Target Names

LILRB2

Alternative Names

CD85 antigen-like family member D antibody; CD85d antibody; CD85d antigen antibody; ILT 4 antibody; ILT-4 antibody; ILT4 antibody; Immunoglobulin like transcript 4 antibody; Immunoglobulin-like transcript 4 antibody; Leukocyte immunoglobulin like receptor 2 antibody; Leukocyte immunoglobulin like receptor subfamily B member 2 antibody; Leukocyte immunoglobulin-like receptor 2 antibody; Leukocyte immunoglobulin-like receptor subfamily B member 2 antibody; Leukocyte immunoglobulin-like receptor; subfamily B (with TM and ITIM domains); member 2 antibody; LILRA6 antibody; LILRB2 antibody; LIR 2 antibody; LIR-2 antibody; LIR2 antibody; LIRb antibody; LIRB2_HUMAN antibody; MIR 10 antibody; MIR-10 antibody; MIR10 antibody; Monocyte/macrophage immunoglobulin like receptor 10 antibody; Monocyte/macrophage immunoglobulin-like receptor 10 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Synthesized peptide derived from the Internal region of Human CD85d.

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Form

Liquid

Tested Applications

WB, ELISA

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:2000
ELISA	1:10000

Protocols

Western Blotting(WB) Protocol
ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles. Involved in the down-regulation of the immune response and the development of tolerance. Recognizes HLA-G in complex with B2M/beta-2 microglobulin and a nonamer self-peptide (peptide-bound HLA-G-B2M) triggering differentiation of type 1 regulatory T cells and myeloid-derived suppressor cells, both of which actively maintain maternal-fetal tolerance. Competes with CD8A for binding to class I MHC antigens. Inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.

Subcellular Location

Cell membrane; Single-pass type I membrane protein.

Tissue Specificity

Expressed in monocytes and at lower levels in myeloid and plasmacytoid dendritic cells. Expressed in tolerogenic IL10-producing dendritic cells. Expressed in myeloid-derived suppressor cells during pregnancy. Detected at low levels in natural killer (NK)

Database Links

HGNC: 6606

OMIM: 604815

STRING: 9606.ENSP00000375629

UniGene: Hs.655652

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Service

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Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Target Therapy

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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