MCM3 Antibody

Datasheet
Code CSB-PA005147
Size US$167
Uniprot No. P25205
Image
  • Western Blot analysis of K562 cells using MCM3 Polyclonal Antibody
Protocols Western Blotting(WB) Protocol
ELISA Protocol
Immunogen Synthesized peptide derived from the Internal region of Human MCM3.
Raised in Rabbit
Species Reactivity Human
Tested Applications WB,ELISA;WB:1/500-1/2000.ELISA:1/20000
Form Liquid
Conjugate Non-conjugated
Storage Buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Alias MCM3; DNA replication licensing factor MCM3; DNA polymerase alpha holoenzyme-associated protein P1; P1-MCM3; RLF subunit beta; p102
Immunogen Species Homo sapiens (Human)
Target Names MCM3
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for DNA replication and cell proliferation.
Subcellular Location Nucleus
Protein Families MCM family
Database Links

HGNC: 6945

OMIM: 602693

KEGG: hsa:4172

STRING: 9606.ENSP00000229854

UniGene: Hs.179565

Pathway Cell cycle

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