NCOA4 Antibody

Code CSB-PA000917
Size US$167
Uniprot No. Q13772
  • Western Blot analysis of 293 cells using ARA70 Polyclonal Antibody
Protocols Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
ELISA Protocol
Immunogen Synthesized peptide derived from the Internal region of Human ARA70.
Raised in Rabbit
Species Reactivity Human,Mouse,Rat
Tested Applications WB,IHC,ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/40000
Form Liquid
Conjugate Non-conjugated
Storage Buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Alias NCOA4; ARA70; ELE1; RFG; Nuclear receptor coactivator 4; NCoA-4; Androgen receptor coactivator 70 kDa protein; 70 kDa AR-activator; 70 kDa androgen receptor coactivator; Androgen receptor-associated protein of 70 kDa; Ret-activating protein
Immunogen Species Homo sapiens (Human)
Target Names NCOA4
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Enhances the androgen receptor transcriptional activity in prostate cancer cells. Ligand-independent coactivator of the peroxisome proliferator-activated receptor (PPAR) gamma.
Involvement in disease A chromosomal aberration involving NCOA4 is found in papillary thyroid carcinomas (PTCs). Inversion inv(10)(q11.2;q11.2) generates the RET/NCOA4 (PTC3) oncogene.
Tissue Specificity Widely expressed. Also detected in adipose tissues and in different cell lines. Isoform Beta is only expressed in testis.
Database Links

HGNC: 7671

OMIM: 601984

KEGG: hsa:8031

STRING: 9606.ENSP00000395465

UniGene: Hs.643658

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