NFE2L2 Antibody

Datasheet
Code CSB-PA003481
Size US$167
Uniprot No. Q16236
Image
  • Western Blot analysis of HuvEc cells using Nrf2 Polyclonal Antibody
  • Western Blot analysis of KB HELA cells using Nrf2 Polyclonal Antibody
Protocols Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
ELISA Protocol
Immunogen Synthesized peptide derived from the C-terminal region of Human Nrf2.
Raised in Rabbit
Species Reactivity Human,Mouse,Rat
Tested Applications WB,IHC,IF,ELISA;WB:1/500-1/2000.IHC:1/100-1/300.IF:1/200-1/1000.ELISA:1/40000
Form Liquid
Conjugate Non-conjugated
Storage Buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Alias NFE2L2; NRF2; Nuclear factor erythroid 2-related factor 2; NF-E2-related factor 2; NFE2-related factor 2; HEBP1; Nuclear factor; erythroid derived 2, like 2
Immunogen Species Homo sapiens (Human)
Target Names NFE2L2
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
References
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Function Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.
Subcellular Location Cytoplasm, cytosol, Nucleus
Protein Families BZIP family, CNC subfamily
Tissue Specificity Widely expressed. Highest expression in adult muscle, kidney, lung, liver and in fetal muscle.
Database Links

HGNC: 7782

OMIM: 600492

KEGG: hsa:4780

STRING: 9606.ENSP00000380252

UniGene: Hs.744006

Pathway Protein processing in endoplasmic reticulum
Cell ageing and metabolism

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