NMT2 Antibody

Datasheet

Code	CSB-PA213831
Size	US$166
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Image	The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using CSB-PA213831(NMT2 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
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Product Details
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Target Background

Product Details

Uniprot No.

O60551

Target Names

NMT2

Alternative Names

EC 2.3.1.97 antibody; Glycylpeptide N tetradecanoyltransferase 2 antibody; Glycylpeptide N-tetradecanoyltransferase 2 antibody; Myristoyl CoA:protein N myristoyltransferase 2 antibody; Myristoyl-CoA:protein N-myristoyltransferase 2 antibody; N-myristoyltransferase 2 antibody; NMT 2 antibody; NMT2 antibody; NMT2_HUMAN antibody; Peptide N myristoyltransferase 2 antibody; Peptide N-myristoyltransferase 2 antibody; Type II N myristoyltransferase antibody; Type II N-myristoyltransferase antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse

Immunogen

Fusion protein of Human NMT2

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form

Liquid

Tested Applications

ELISA,IHC

Recommended Dilution

Application	Recommended Dilution
ELISA	1:1000-1:2000
IHC	1:25-1:100

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins.

Gene References into Functions

ligand binding properties of the NMT/ACBD6 complex can explain how the NMT reaction can proceed in the presence of the very abundant competitive substrate, C(16)-CoA. PMID: 26621918
induction of NMT2 may play a central role in dioxin carcinogenicity. PMID: 11731439
NMT1 and NMT2 have only partially overlapping functions; NMT1 is critical for tumor cell proliferation PMID: 16123142
Involved in progression and regulation of telomerase PMID: 16364039
Protein-protein interaction of NMTs revealed that m-calpain interacts with NMT1 while caspase-3 interacts with NMT2. PMID: 16530191
Disruption of the gene for NMT2 by a t(8;10) translocation in a male with hypogonadism. PMID: 17568424
Nef is preferentially myristoylated by NMT2, suggesting that selective inhibition of NMT2 may provide a novel means of blocking HIV virulence. PMID: 18089753

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Subcellular Location

Cytoplasm. Membrane; Peripheral membrane protein.

Protein Families

NMT family

Database Links

HGNC: 7858

OMIM: 603801

KEGG: hsa:9397

STRING: 9606.ENSP00000367407

UniGene: Hs.60339

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Email: [email protected]
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Service

Phage Display Service

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Protein Service

Gene Synthesis Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Target Therapy

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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