NMT2 Antibody

Code CSB-PA015901DSR2HU
Size US$166
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  • Western blot
    All lanes: NMT2 antibody at 4.99μg/ml
    Lane 1: Human placenta tissue
    Lane 2: K562 whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 57 kDa
    Observed band size: 57 kDa

  • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA015901DSR2HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA015901DSR2HU at dilution of 1:100

  • Immunoprecipitating NMT2 in HepG2 whole cell lysate
    Lane 1: Rabbit control IgG instead of (1μg) instead of CSB-PA015901DSR2HU in HepG2 whole cell lysate. For western blotting, a HRP-conjugated anti-rabbit IgG, specific to the non-reduced form of IgG was used as the Secondary antibody (1/50000)
    Lane 2: CSB-PA015901DSR2HU (4μg) + HepG2 whole cell lysate (500μg)
    Lane 3: HepG2 whole cell lysate (20μg)

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) NMT2 Polyclonal antibody
Uniprot No.
Target Names
NMT2
Alternative Names
EC 2.3.1.97 antibody; Glycylpeptide N tetradecanoyltransferase 2 antibody; Glycylpeptide N-tetradecanoyltransferase 2 antibody; Myristoyl CoA:protein N myristoyltransferase 2 antibody; Myristoyl-CoA:protein N-myristoyltransferase 2 antibody; N-myristoyltransferase 2 antibody; NMT 2 antibody; NMT2 antibody; NMT2_HUMAN antibody; Peptide N myristoyltransferase 2 antibody; Peptide N-myristoyltransferase 2 antibody; Type II N myristoyltransferase antibody; Type II N-myristoyltransferase antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Glycylpeptide N-tetradecanoyltransferase 2 protein (1-120AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, WB, IHC, IP
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
IHC 1:20-1:200
IP 1:200-1:2000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins.
Gene References into Functions
  1. ligand binding properties of the NMT/ACBD6 complex can explain how the NMT reaction can proceed in the presence of the very abundant competitive substrate, C(16)-CoA. PMID: 26621918
  2. induction of NMT2 may play a central role in dioxin carcinogenicity. PMID: 11731439
  3. NMT1 and NMT2 have only partially overlapping functions; NMT1 is critical for tumor cell proliferation PMID: 16123142
  4. Involved in progression and regulation of telomerase PMID: 16364039
  5. Protein-protein interaction of NMTs revealed that m-calpain interacts with NMT1 while caspase-3 interacts with NMT2. PMID: 16530191
  6. Disruption of the gene for NMT2 by a t(8;10) translocation in a male with hypogonadism. PMID: 17568424
  7. Nef is preferentially myristoylated by NMT2, suggesting that selective inhibition of NMT2 may provide a novel means of blocking HIV virulence. PMID: 18089753

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Subcellular Location
Cytoplasm. Membrane; Peripheral membrane protein.
Protein Families
NMT family
Database Links

HGNC: 7858

OMIM: 603801

KEGG: hsa:9397

STRING: 9606.ENSP00000367407

UniGene: Hs.60339

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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