NUP210 Antibody

Datasheet

Code	CSB-PA016195GA01HU
Size	$600
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Product Details
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Target Background

Product Details

Uniprot No.

Q8TEM1

Target Names

NUP210

Alternative Names

FLJ22389 antibody; GP 210 antibody; KIAA0906 antibody; Nuclear envelope pore membrane protein POM 210 antibody; Nuclear pore membrane glycoprotein 210 antibody; Nuclear pore protein gp210 antibody; Nucleoporin 210 antibody; Nucleoporin 210kDa antibody; Nucleoporin Nup210 antibody; Nucleoporin210 antibody; NUP 210 antibody; Nup210 antibody; PO210_HUMAN antibody; POM 210 antibody; POM210 antibody; Pore membrane protein of 210 kDa antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Human NUP210

Immunogen Species

Homo sapiens (Human)

Isotype

IgG

Purification Method

Antigen Affinity purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.

Tested Applications

ELISA,WB

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function

Nucleoporin essential for nuclear pore assembly and fusion, nuclear pore spacing, as well as structural integrity.

Gene References into Functions

solution structure of the C-terminal domain PMID: 12653556
gp210 plays critical roles at the nuclear membrane PMID: 14517331
WT1 is probably not regulating GP210 expression, in spite of binding sites for WT1 PMID: 15613247
Quantitation of serusm anti-gp210-C-terminal peptide antibodies is useful for monitoring the effect of ursodeoxycholic acid and for the early identification of patients at high risk for end-stage hepatic failure. PMID: 15710222
The increased expression of gp210 in small bile ducts is possibly involved in autoimmune response to gp210 leading to the progression to end-stage hepatic failure in primary biliary cirrhosis . PMID: 16337775
Double knockdowns of gp210 in HeLa cells suggest that nuclear pore complexes can assemble or at least persist in a gp210-free form. PMID: 16702234

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Subcellular Location

Nucleus, nuclear pore complex. Nucleus membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein.

Protein Families

NUP210 family

Tissue Specificity

Ubiquitous expression, with highest levels in lung, liver, pancreas, testis, and ovary, intermediate levels in brain, kidney, and spleen, and lowest levels in heart and skeletal muscle.

Database Links

HGNC: 30052

OMIM: 607703

KEGG: hsa:23225

STRING: 9606.ENSP00000254508

UniGene: Hs.475525

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Protein Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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