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PDHA2 Antibody

Datasheet
Code CSB-PA017716ESR1HU
Size US$166
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Image
  • Western Blotting(WB) - PDHA2 Antibody

    Western blot
    All lanes: PDHA2 antibody at 1.62 μg/ml
    Lane 1: Mouse gonadal tissue
    Lane 2: 293T whole cell lysate
    Lane 3: A549 whole cell lysate
    Lane 4: HepG2 whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 43 kDa
    Observed band size: 43 kDa

  • Immunohistochemistry(IHC) 1- PDHA2 Antibody

    Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA017716ESR1HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) PDHA2 Polyclonal antibody
Uniprot No.
P29803
Target Names
PDHA2
Alternative Names
PDHA2 antibody; PDHAL antibody; Pyruvate dehydrogenase E1 component subunit alpha antibody; testis-specific form antibody; mitochondrial antibody; EC 1.2.4.1 antibody; PDHE1-A type II antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial protein (119-388AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
IHC 1:20-1:200
Protocols
ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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PDHA2 Antibodies

PDHA2 Proteins

Customer Reviews and Q&A

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Target Background

Function
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.
Gene References into Functions
  1. Our results indicated that miR215p targeted PDHA1 to regulate a metabolic switch and cancer progression in gastric cancer, and reveal the potential role of the miR215p/PDHA1 axis in gastric cancer treatment PMID: 30226598
  2. Methylation of the PDHA2 coding region can inhibit gene transcription. PMID: 22675509
  3. it is the full demethylation of the CpG island located in the coding region that seems to play a crucial role upon PDHA2 gene transcription in testis. PMID: 20005141
Subcellular Location
Mitochondrion matrix.
Tissue Specificity
Testis. Expressed in postmeiotic spermatogenic cells.
Database Links

HGNC: 8807

OMIM: 179061

KEGG: hsa:5161

STRING: 9606.ENSP00000295266

UniGene: Hs.131361

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Related Articles
Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?
Related pathways
HIF-1 signaling pathway Glucagon signaling pathway
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