PDHA2 Antibody

Code CSB-PA017716ESR2HU
Size US$166
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Image
  • Western blot
    All lanes: PDHA2 antibody at 1.9µg/ml
    Lane 1: Mouse gonadal tissue
    Lane 2: 293T whole cell lysate
    Lane 3: A549 whole cell lysate
    Lane 4: HepG2 whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 43 kDa
    Observed band size: 43 kDa

  • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA017716ESR2HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA017716ESR2HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) PDHA2 Polyclonal antibody
Uniprot No.
Target Names
PDHA2
Alternative Names
PDHA2 antibody; PDHAL antibody; Pyruvate dehydrogenase E1 component subunit alpha antibody; testis-specific form antibody; mitochondrial antibody; EC 1.2.4.1 antibody; PDHE1-A type II antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial protein (119-388AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.
Gene References into Functions
  1. Our results indicated that miR215p targeted PDHA1 to regulate a metabolic switch and cancer progression in gastric cancer, and reveal the potential role of the miR215p/PDHA1 axis in gastric cancer treatment PMID: 30226598
  2. Methylation of the PDHA2 coding region can inhibit gene transcription. PMID: 22675509
  3. it is the full demethylation of the CpG island located in the coding region that seems to play a crucial role upon PDHA2 gene transcription in testis. PMID: 20005141
Subcellular Location
Mitochondrion matrix.
Tissue Specificity
Testis. Expressed in postmeiotic spermatogenic cells.
Database Links

HGNC: 8807

OMIM: 179061

KEGG: hsa:5161

STRING: 9606.ENSP00000295266

UniGene: Hs.131361

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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