PFKFB1/PFKFB4 Antibody

Code CSB-PA063311
Size US$297
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  • Western blot analysis of extracts from HeLa cells, HepG2 cells, COLO205 cells and 293 cells, using PFKFB1/4 antibody.
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) PFKFB1/PFKFB4 Polyclonal antibody
Uniprot No.
Target Names
PFKFB1/PFKFB4
Alternative Names
6 phosphofructo 2 kinase/fructose 2 6 biphosphatase 1 antibody; 6-bisphosphatase antibody; 6-P2ase 1 antibody; 6-P2ASE liver isozyme antibody; 6PF 2 K/Fru 2 6 P2ASE liver isozyme antibody; 6PF 2 K/Fru 2,6 P2ase 1 antibody; 6PF-2-K/Fru-2 antibody; F261_HUMAN antibody; F6PK antibody; Fructose 2 6 bisphosphatase antibody; Fructose 6 phosphate 2 kinase:fructose 2 6 bisphosphatase antibody; Fructose-2 antibody; HL2K antibody; MGC116715 antibody; MGC116717 antibody; PFK/FBPase 1 antibody; PFKFB 1 antibody; Pfkfb1 antibody; PFRX antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthesized peptide derived from internal of Human PFKFB1/4.
Immunogen Species
Homo sapiens (Human)
Clonality
Polyclonal
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications
ELISA,WB
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:3000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Synthesis and degradation of fructose 2,6-bisphosphate.
Gene References into Functions
  1. Insulin resistance in obese boys leads to up-regulation of INSIG2 gene expression as well as to down-regulation of PFKFB1, PFKFB3, and HK2 genes in the blood cells as compared to obese patients with normal insulin sensitivity. PMID: 26827442
  2. Results describe structural differences between two isozymes of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase from liver and testis. PMID: 12379646
Protein Families
Phosphoglycerate mutase family
Tissue Specificity
Liver.
Database Links

HGNC: 8872

OMIM: 311790

KEGG: hsa:5207

STRING: 9606.ENSP00000364145

UniGene: Hs.444304

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7505 Fannin St., Ste 610, Room 322 (CUBIO Innovation Center), Houston, TX 77054, USA
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