PHKA1 Antibody

Datasheet

Code	CSB-PA566650
Size	US$297
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Image	Western blot analysis of extracts from Jurkat cells and COLO205 cells, using KPB1/2 antibody. Immunofluorescence analysis of HeLa cells, using KPB1/2 antibody.
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) PHKA1 Polyclonal antibody

Uniprot No.

P46020

Target Names

PHKA1

Alternative Names

5330411D17 antibody; 9830108K24Rik antibody; kinase PHKA1 antibody; KPB1 antibody; KPB1_HUMAN antibody; MGC132604 antibody; Pcyt1b antibody; PHKA antibody; PHKA1 antibody; Phosphorylase b kinase regulatory subunit alpha antibody; Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform antibody; Phosphorylase kinase alpha M subunit antibody; phosphorylase kinase, alpha 1 (muscle) antibody; RP23 210E20.1 antibody; skeletal muscle isoform antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthesized peptide derived from internal of Human KPB1/2.

Immunogen Species

Homo sapiens (Human)

Clonality

Polyclonal

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Tested Applications

ELISA,WB,IF

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:3000
IF	1:100-1:500

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin.

Gene References into Functions

muscle PHKA deficiency may present as an almost asymptomatic condition, despite a mild impairment of muscle PMID: 22238410
alpha- and beta-subunits possess amino-terminal glucoamylase-like domains and suggests that they might possess a previously overlooked amylase activity PMID: 12876330
X-linked PHK deficiency causes a mild metabolic myopathy with blunted muscle glycogen breakdown and impaired lactate production during dynamic exercise, which impairs oxidative capacity only marginally PMID: 18401027

Involvement in disease

Glycogen storage disease 9D (GSD9D)

Subcellular Location

Cell membrane; Lipid-anchor; Cytoplasmic side.

Protein Families

Phosphorylase b kinase regulatory chain family

Tissue Specificity

Muscle specific. Isoform 1 is predominant in vastus lateralis muscle. Isoform 2 predominates slightly in heart, and it predominates clearly in the other tissues tested.

Database Links

HGNC: 8925

OMIM: 300559

KEGG: hsa:5255

STRING: 9606.ENSP00000362643

UniGene: Hs.201379

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Calcium signaling pathway Glucagon signaling pathway Insulin signaling pathway

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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