PLPP2 Antibody

Datasheet

Code	CSB-PA018416LA01HU
Size	US$166
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Image	Western blot All lanes: PLPP2 antibody at 8µg/ml + MCF-7 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 33, 35, 27 kDa Observed band size: 33 kDa Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA018416LA01HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA018416LA01HU at dilution of 1:100 Immunofluorescent analysis of A549 cells using CSB-PA018416LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) PLPP2 Polyclonal antibody

Uniprot No.

O43688

Target Names

PLPP2

Alternative Names

PLPP2; LPP2; PPAP2C; Phospholipid phosphatase 2; Lipid phosphate phosphohydrolase 2; PAP2-gamma; PAP2-G; Phosphatidate phosphohydrolase type 2c; Phosphatidic acid phosphatase 2c; PAP-2c; PAP2c

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Phospholipid phosphatase 2 protein (109-162AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The PLPP2 Antibody (Product code: CSB-PA018416LA01HU) is Non-conjugated. For PLPP2 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA018416LB01HU	PLPP2 Antibody, HRP conjugated	ELISA
FITC	CSB-PA018416LC01HU	PLPP2 Antibody, FITC conjugated
Biotin	CSB-PA018416LD01HU	PLPP2 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, WB, IHC, IF

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:2000
IHC	1:20-1:200
IF	1:50-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Magnesium-independent phospholipid phosphatase that catalyzes the dephosphorylation of a variety of glycerolipid and sphingolipid phosphate esters including phosphatidate/PA, lysophosphatidate/LPA, sphingosine 1-phosphate/S1P and ceramide 1-phosphate/C1P. Has no apparent extracellular phosphatase activity and therefore most probably acts intracellularly. Also acts on N-oleoyl ethanolamine phosphate/N-(9Z-octadecenoyl)-ethanolamine phosphate, a potential physiological compound. Through dephosphorylation of these bioactive lipid mediators produces new bioactive compounds and may regulate signal transduction in different cellular processes (Probable). Indirectly regulates, for instance, cell cycle G1/S phase transition through its phospholipid phosphatase activity.

Gene References into Functions

identified a novel and specific role for LPP2 activity and bioactive lipids in regulating cell cycle progression PMID: 16467304
endogenous LPP2 and LPP3 form homo- and hetero-oligomers, which differ in their subcellular localization and which may confer differing spatial regulation of phosphatidic acid and sphingosine 1-phosphate signalling PMID: 18215144

Subcellular Location

Membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Early endosome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.

Protein Families

PA-phosphatase related phosphoesterase family

Tissue Specificity

Found mainly in brain, pancreas and placenta.

Database Links

HGNC: 9230

OMIM: 607126

KEGG: hsa:8612

STRING: 9606.ENSP00000329697

UniGene: Hs.465506

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Fc gamma R-mediated phagocytosis Oxidative Phosphorylation Phospholipase D signaling pathway

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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