PPP2R5E Antibody, FITC conjugated

Datasheet

Code	CSB-PA619075LC01HU
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) PPP2R5E Polyclonal antibody

Uniprot No.

Q16537

Target Names

PPP2R5E

Alternative Names

2A5E_HUMAN antibody; Epsilon isoform of regulatory subunit B56 protein phosphatase 2A antibody; PP2A B subunit B' epsilon antibody; PP2A B subunit B' epsilon isoform antibody; PP2A B subunit B56 epsilon antibody; PP2A B subunit B56 epsilon isoform antibody; PP2A B subunit isoform B''-epsilon antibody; PP2A B subunit isoform B'-epsilon antibody; PP2A B subunit isoform B56-epsilon antibody; PP2A B subunit isoform PR61-epsilon antibody; PP2A B subunit isoform R5-epsilon antibody; PP2A B subunit PR61 epsilon antibody; PP2A B subunit PR61 epsilon isoform antibody; PP2A B subunit R5 epsilon antibody; PP2A B subunit R5 epsilon isoform antibody; PPP2R5E antibody; Protein phosphatase 2 regulatory subunit B (B56) epsilon isoform antibody; Protein phosphatase 2 regulatory subunit B' epsilon antibody; Protein phosphatase 2 regulatory subunit B' epsilon isoform antibody; Regulatory subunit B of protein phosphatase 2 epsilon isoform antibody; Serine/threonine protein phosphatase 2A 56 kDa regulatory subunit epsilon antibody; Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform protein (2-149AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

FITC

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

Gene References into Functions

results suggest that the PPP2R5E phosphatase may contribute to microtubule organization by stabilizing MTCL1. PMID: 27521566
PP2A holoenzyme containing B56 is responsible for the dephosphorylation of gamma-H2AX and regulation of DNA repair of double strand breaks induced by camptothecin. PMID: 25772433
the significance of miR-23a and PPP2R5E in the proliferation and apoptosis of gastric cancer cells PMID: 24997345
Downregulation of PPP2R5E affects the oncogenic potential of leukemic cells. PMID: 23812941
identified the phosphorylation of hSgo2 by Aurora B at the N-terminal coiled-coil region and the middle region, and showed that these phosphorylations separately promote binding of hSgo2 to PP2A and MCAK PMID: 20889715
The PPP2R5E gene is identified as harboring genetic variants that can affect human cancer and are possibly under evolutionary selection pressure. PMID: 19773383

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Subcellular Location

Cytoplasm.

Protein Families

Phosphatase 2A regulatory subunit B56 family

Database Links

HGNC: 9313

OMIM: 601647

KEGG: hsa:5529

STRING: 9606.ENSP00000337641

UniGene: Hs.334868

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Related pathways

PI3K-Akt signaling pathway AMPK signaling Sphingolipid signaling pathway

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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