PYGL Antibody

Code CSB-PA185772
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA185772(PYGL Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA185772(PYGL Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
  • Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane 1-2: PC3 cells, human fetal liver tissue, Primary antibody: CSB-PA185772(PYGL Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds
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Product Details

Uniprot No.
Target Names
PYGL
Alternative Names
Glycogen phosphorylase antibody; Glycogen phosphorylase L antibody; Glycogen phosphorylase liver antibody; Glycogen phosphorylase liver form antibody; GSD6 antibody; Hers disease; glycogen storage disease type VI antibody; liver form antibody; OTTHUMP00000233649 antibody; OTTHUMP00000233651 antibody; Phosphorylase glycogen liver antibody; Pygl antibody; PYGL_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Fusion protein of Human PYGL
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,WB,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:1000-1:2000
WB 1:200-1:1000
IHC 1:25-1:100
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
Gene References into Functions
  1. Susceptibility to excessive liver glycogen storage in patients with type 1 diabetes. PMID: 15223230
  2. Deficiency of liver glycogen phosphorylase is predominantly the result of missense mutations affecting enzyme activity. There are no common mutations and the severity of clinical symptoms varies significantly. PMID: 17705025
Involvement in disease
Glycogen storage disease 6 (GSD6)
Subcellular Location
Cytoplasm, cytosol.
Protein Families
Glycogen phosphorylase family
Database Links

HGNC: 9725

OMIM: 232700

KEGG: hsa:5836

STRING: 9606.ENSP00000216392

UniGene: Hs.282417

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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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