PYGL Antibody

Code CSB-PA019122EA01HU
Size US$166
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Image
  • Western blot
    All lanes: PYGL antibody at 2µg/ml
    Lane 1: 293T whole cell lysate
    Lane 2: HepG2 whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 98, 94 kDa
    Observed band size: 98 kDa

  • Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA019122EA01HU at dilution of 1:20

  • Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA019122EA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA019122EA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) PYGL Polyclonal antibody
Uniprot No.
Target Names
PYGL
Alternative Names
Glycogen phosphorylase antibody; Glycogen phosphorylase L antibody; Glycogen phosphorylase liver antibody; Glycogen phosphorylase liver form antibody; GSD6 antibody; Hers disease; glycogen storage disease type VI antibody; liver form antibody; OTTHUMP00000233649 antibody; OTTHUMP00000233651 antibody; Phosphorylase glycogen liver antibody; Pygl antibody; PYGL_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Glycogen phosphorylase, liver form protein (2-846AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The PYGL Antibody (Product code: CSB-PA019122EA01HU) is Non-conjugated. For PYGL Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA019122EB01HU PYGL Antibody, HRP conjugated ELISA
FITC CSB-PA019122EC01HU PYGL Antibody, FITC conjugated
Biotin CSB-PA019122ED01HU PYGL Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
Gene References into Functions
  1. Susceptibility to excessive liver glycogen storage in patients with type 1 diabetes. PMID: 15223230
  2. Deficiency of liver glycogen phosphorylase is predominantly the result of missense mutations affecting enzyme activity. There are no common mutations and the severity of clinical symptoms varies significantly. PMID: 17705025
Involvement in disease
Glycogen storage disease 6 (GSD6)
Subcellular Location
Cytoplasm, cytosol.
Protein Families
Glycogen phosphorylase family
Database Links

HGNC: 9725

OMIM: 232700

KEGG: hsa:5836

STRING: 9606.ENSP00000216392

UniGene: Hs.282417

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