Phospho-ELK1 (T417) Antibody

Code CSB-PA008013
Size US$167
Uniprot No. P19419
Protocols Immunohistochemistry (IHC) Protocol
Immunoprecipitation (IP) Protocol
ELISA Protocol
Immunogen Synthesized peptide derived from Human Elk-1 around the phosphorylation site of T417.
Raised in Rabbit
Species Reactivity Human,Mouse,Rat
Tested Applications IHC,IP,ELISA;IHC:1/100-1/300.IP:2-5ug/mglysate.ELISA:1/10000
Form Liquid
Conjugate Non-conjugated
Storage Buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Alias ELK1; ETS domain-containing protein Elk-1
Immunogen Species Homo sapiens (Human)
Target Names ELK1
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Transcription factor that binds to purine-rich DNA sequences. Forms a ternary complex with SRF and the ETS and SRF motifs of the serum response element (SRE) on the promoter region of immediate early genes such as FOS and IER2. Induces target gene transcription upon JNK-signaling pathway stimulation (By similarity).
Subcellular Location Nucleus
Protein Families ETS family
Tissue Specificity Lung and testis.
Database Links

HGNC: 3321

OMIM: 311040

KEGG: hsa:2002

STRING: 9606.ENSP00000247161

UniGene: Hs.181128

Pathway ErbB signaling pathway
MAPK signaling pathway
Focal adhesion
MAPK Erk pathway
Ras signaling pathway
Insulin signaling pathway

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