S100A3 Antibody

Datasheet

Code	CSB-PA020631ESR2HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA020631ESR2HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) S100A3 Polyclonal antibody

Uniprot No.

P33764

Target Names

S100A3

Alternative Names

Protein S 100E antibody; Protein S-100E antibody; Protein S100 A3 antibody; Protein S100-A3 antibody; S100 calcium binding protein A3 antibody; S100 calcium-binding protein A3 antibody; S100a3 antibody; S100E antibody; S10A3_HUMAN antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Protein S100-A3 protein (1-101AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Binds both calcium and zinc. May be involved in calcium-dependent cuticle cell differentiation, hair shaft and hair cuticular barrier formation.

Gene References into Functions

S100A3 expression is significantly upregulated in human masticatory mucosa during wound healing PMID: 28005267
One disulfide bridge is between Cys30 in the N-terminal pseudo-EF-hand and Cys68 in the C-terminal EF-hand (SS1), and another disulfide bridge attaches Cys99 in the C-terminal coil structure to Cys81 in helix IV (SS2). PMID: 21377473
crystal structure of S100A3 at 1.7-A resolution PMID: 12045193
structure was solved by MIRAS phasing PMID: 12136135
Purification and characterization of the S100A3 protein from human hair cuticles. PMID: 12470658
cytoplasmic S100A3 within the cuticular layer is mostly co-localized with the type III isoform of peptidylarginine deiminase (PAD3) PMID: 18083705

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Subcellular Location

Cytoplasm.

Protein Families

S-100 family

Tissue Specificity

Skin specific, specifically expressed at the inner endocuticle of hair fibers.

Database Links

HGNC: 10493

OMIM: 176992

KEGG: hsa:6274

STRING: 9606.ENSP00000357701

UniGene: Hs.557609

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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