S100A3 Antibody

Code CSB-PA020631GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
S100A3
Alternative Names
Protein S 100E antibody; Protein S-100E antibody; Protein S100 A3 antibody; Protein S100-A3 antibody; S100 calcium binding protein A3 antibody; S100 calcium-binding protein A3 antibody; S100a3 antibody; S100E antibody; S10A3_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human S100A3
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Binds both calcium and zinc. May be involved in calcium-dependent cuticle cell differentiation, hair shaft and hair cuticular barrier formation.
Gene References into Functions
  1. S100A3 expression is significantly upregulated in human masticatory mucosa during wound healing PMID: 28005267
  2. One disulfide bridge is between Cys30 in the N-terminal pseudo-EF-hand and Cys68 in the C-terminal EF-hand (SS1), and another disulfide bridge attaches Cys99 in the C-terminal coil structure to Cys81 in helix IV (SS2). PMID: 21377473
  3. crystal structure of S100A3 at 1.7-A resolution PMID: 12045193
  4. structure was solved by MIRAS phasing PMID: 12136135
  5. Purification and characterization of the S100A3 protein from human hair cuticles. PMID: 12470658
  6. cytoplasmic S100A3 within the cuticular layer is mostly co-localized with the type III isoform of peptidylarginine deiminase (PAD3) PMID: 18083705

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Subcellular Location
Cytoplasm.
Protein Families
S-100 family
Tissue Specificity
Skin specific, specifically expressed at the inner endocuticle of hair fibers.
Database Links

HGNC: 10493

OMIM: 176992

KEGG: hsa:6274

STRING: 9606.ENSP00000357701

UniGene: Hs.557609

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