SEC24A Antibody

Code CSB-PA020950GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
SEC24A
Alternative Names
SEC24A antibody; Protein transport protein Sec24A antibody; SEC24-related protein A antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human SEC24A
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC,IF
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex. Plays a central role in cargo selection within the COPII complex and together with SEC24B may have a different specificity compared to SEC24C and SEC24D. May package preferentially cargos with cytoplasmic DxE or LxxLE motifs and may also recognize conformational epitopes.
Gene References into Functions
  1. the association between Kv1.3 and the COPII cargo adaptor subunit isoform Sec24a PMID: 26156069
  2. CstA, a secreted Brucella protein specifically interacts with human Sec24A. PMID: 22820839
  3. Sec24 isoforms expand the repertoire of cargo for signal-mediated ER export, but are in part functionally redundant. PMID: 17255961
Subcellular Location
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytosol.
Protein Families
SEC23/SEC24 family, SEC24 subfamily
Database Links

HGNC: 10703

OMIM: 607183

KEGG: hsa:10802

STRING: 9606.ENSP00000381823

UniGene: Hs.595540

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