SIRPB1 Antibody

Code CSB-PA021335LA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human thyroid tissue using CSB-PA021335LA01HU at dilution of 1:100
  • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA021335LA01HU at dilution of 1:100
  • Immunofluorescent analysis of Hela cells using CSB-PA021335LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • Western Blot
    Positive WB detected in: THP-1 whole cell lysate , A549 whole cell lysate , PC-3whole cell lysate , JK whole cell lysate ,mouse heart tissue lysate
    All lanes: SIRPB1 antibody at 1:1000
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 44 kDa
    Observed band size: 44 kDa
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) SIRPB1 Polyclonal antibody
Uniprot No.
Target Names
SIRPB1
Alternative Names
SIRPB1 antibody; Signal-regulatory protein beta-1 antibody; SIRP-beta-1 antibody; CD172 antigen-like family member B antibody; CD antigen CD172b antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human Signal-regulatory protein beta-1 protein (30-371AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The SIRPB1 Antibody (Product code: CSB-PA021335LA01HU) is Non-conjugated. For SIRPB1 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA021335LB01HU SIRPB1 Antibody, HRP conjugated ELISA
FITC CSB-PA021335LC01HU SIRPB1 Antibody, FITC conjugated
Biotin CSB-PA021335LD01HU SIRPB1 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC, IF
Recommended Dilution
Application Recommended Dilution
WB 500-2000
IHC 1:20-1:200
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Participates also in the recruitment of tyrosine kinase SYK. Triggers activation of myeloid cells when associated with TYROBP.
Gene References into Functions
  1. SIRPB1 copy-number polymorphism was significantly associated with impulsive-disinhibited personality scores in a dose-dependent manner. PMID: 25039969
  2. SIRPbeta1 is a novel IFN-induced microglial receptor that supports clearance of neural debris and Abeta aggregates by stimulating phagocytosis. PMID: 19893026
  3. SIRP beta 1 is a disulfide-linked homodimer in leukocytes that regulates neutrophil transepithelial migration PMID: 16081415
  4. This protein has been found differentially expressed in the temporal lobe from patients with schizophrenia. PMID: 19034380
Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Tissue Specificity
Detected in monocytes and dendritic cells.
Database Links

HGNC: 15928

OMIM: 603889

UniGene: Hs.664861

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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