Recombinant Human Signal-regulatory protein beta-1(SIRPB1),partial

Code CSB-YP021335HU
Product Type Recombinant Protein
Size US$2959
Uniprot No. O00241
Relevance Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Participates also in the recruitment of tyrosine kinase SYK.
Image
  • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Storage Buffer Tris-based buffer,50% glycerol
Alias SIRP-beta-1 Alternative name(s): CD172 antigen-like family member B CD_antigen: CD172b
Species Homo sapiens (Human)
Purity Greater than 90% as determined by SDS-PAGE.
Sequence EDELQVIQPEKSVSVAAGESATLRCAMTSLIPVGPIMWFRGAGAGRELIYNQKEGHFPRVTTVSELTKRNNLDFSISISNITPADAGTYYCVKFRKGSPDDVEFKSGAGTELSVRAKPSAPVVSGPAVRATPEHTVSFTCESHGFSPRDITLKWFKNGNELSDFQTNVDPAGDSVSYSIHSTARVVLTRGDVHSQVICEIAHITLQGDPLRGTANLSEAIRVPPTLEVTQQPMRAENQANVTCQVSNFYPRGLQLTWLENGNVSRTETASTLIENKDGTYNWMSWLLVNTCAHRDDVVLTCQVEHDGQQAVSKSYALEISAHQKEHGSDITHEAALAPTAPL
Research Area Others
Source Yeast
Gene Names SIRPB1
Protein Names Recommended name: Signal-regulatory protein beta-1 Short name= SIRP-beta-1 Alternative name(s): CD172 antigen-like family member B CD_antigen= CD172b
Expression Region 30-371aa
Tag Info N-terminal 6xHis-tagged
Mol. Weight 39.3kDa
Protein Description Partial
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Participates also in the recruitment of tyrosine kinase SYK.
Subcellular Location Membrane, Single-pass type I membrane protein
Tissue Specificity Detected in monocytes and dendritic cells.
Database Links

HGNC: 15928

OMIM: 603889

UniGene: Hs.664861

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