TEAD3 Antibody

Code CSB-PA904251
Size US$297
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  • Western blot analysis of extracts from Jurkat cells, using TEAD3 antibody.
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) TEAD3 Polyclonal antibody
Uniprot No.
Target Names
Alternative Names
DTEF 1 antibody; DTEF-1 antibody; DTEF1 antibody; ETFR 1 antibody; ETFR1 antibody; TEA domain family member 3 antibody; TEA domain family member 5 antibody; TEAD 3 antibody; TEAD-3 antibody; Tead3 antibody; TEAD3_HUMAN antibody; TEAD5 antibody; TEF 5 antibody; TEF5 antibody; Transcriptional enhancer factor 5 antibody; Transcriptional enhancer factor TEF 5 (DTEF 1) antibody; Transcriptional enhancer factor TEF 5 antibody; Transcriptional enhancer factor TEF-5 antibody
Raised in
Species Reactivity
Synthesized peptide derived from internal of Human TEAD3.
Immunogen Species
Homo sapiens (Human)
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
It differs from different batches. Please contact us to confirm it.
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:3000
Troubleshooting and FAQs
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to multiple functional elements of the human chorionic somatomammotropin-B gene enhancer.
Gene References into Functions
  1. Sequences at the 9p21.3 risk locus disrupt TEAD factor binding and TEAD3-dependent TGF-beta induction of p16 in HAoSMCs. TEAD3 overexpression induced p16 in HAoSMCs homozygous for the nonrisk coronary disease allele, but not for the risk allele. PMID: 26487755
  2. Transcription enhancer factor-5 and the GATA-like protein act in a coordinate manner to determine the placental-specific expression of the human 3beta-hydroxysteroid dehydrogenase/isomerase I enzyme PMID: 15131259
  3. The paper described that the translation initiation codon for the TEF-5 protein was a non-AUG (AUA) codon. PMID: 10379887
  4. The paper described that the translation initiation codon for the TEF-5 protein was a non-AUG (ATA) codon. PMID: 9148898
Subcellular Location
Tissue Specificity
Preferentially expressed in the placenta.
Database Links

HGNC: 11716

OMIM: 603170

KEGG: hsa:7005

STRING: 9606.ENSP00000345772

UniGene: Hs.485205

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