TEAD3

Transcriptional enhancer factor TEF-5 is a protein in humans that is encoded by TEAD3 gene. Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to multiple functional elements of the human chorionic somatomammotropin-B gene enhancer.

TEAD3 Antibodies

TEAD3 Antibodies for Homo sapiens (Human)

TEAD3 Proteins

TEAD3 Proteins for Mus musculus (Mouse)

TEAD3 Proteins for Gallus gallus (Chicken)

TEAD3 Proteins for Homo sapiens (Human)

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